刘巍,肿瘤学博士,主任医师、教授,博士生导师,中组部“万人计划”百千万工程领军人才,国务院政府特殊津贴专家,新世纪百千万人才工程国家级人选,北京市医管局“使命人才”计划负责人。
主要社会兼职:
中国医疗保健国际交流促进会肿瘤姑息治疗与人文关怀分会名誉主任委员 第一届委员会主任委员;
中国抗癌协会常务理事 副秘书长;
中国抗癌协会癌症康复与姑息治疗专业委员会常委;
中国抗癌协会肿瘤临床化疗专业委员会常委;
中华医学会肿瘤学分会支持与康复学组副组长;
中国抗癌协会临床肿瘤学会(CSCO)理事;
中国抗癌协会临床肿瘤学会(CSCO)头颈肿瘤专业委员会委员;
癌症支持疗法多国协会 (MASCC)会员;
卫健委“癌痛规范化治疗示范病房”评审专家;
中国博士后科学基金会评审专家;
国家自然科学基金评审专家
同时兼任《Annals of Oncology》中文版(结直肠癌)、《Journal of Thoracic
Oncology》(JTO)中文版、《中国肿瘤临床》、《中国肿瘤防治杂志》、等期刊编委或审稿专家。
作为中心及科室主任,三十多年来,一直从事肿瘤学临床、教学和科研工作,具有丰富的临床经验和较强的科研能力,长期致力于常见恶性肿瘤内科诊治、规范化、个体化及综合治疗,支持/姑息治疗的临床和基础研究,取得了较为突出的成绩。获得国家自然科学基金以及省部级科研资助项目10余项,先后以第一作者或通讯作者在SCI索引期刊及专业核心期刊发表论文共计200余篇,担任主编主译著作6部。作为主研人获得省部级科技进步二等奖1项、三等奖4项。教学工作上,追求严谨的治学作风,共培养博士研究生21名,硕士研究生49名。重视传授肿瘤支持/姑息治疗及人文关怀理念,牵头举办多场肿瘤支持/姑息治疗研讨会及工作坊,倡导人文医学,为培养综合性专业人才以及推动多学科协作的肿瘤支持/姑息医学事业的发展作出了突出的贡献。
近年来,探索并实施早期支持/姑息治疗模式,并帮助肿瘤患者减轻身、心、社、灵负担及提升生活质量,以期更好地为肿瘤患者提供医疗照护服务的理论依据;同时依托北京大学肿瘤医院头颈肿瘤MDT团队,对每位患者进行综合评价,并结合患者的经济状况、文化程度、患者和家属的意愿及治疗后可能对患者的社会状况、心理所造成的影响等,制定适合个体及家庭的治疗方案并做出有意义的探索和研究。
发表论文
先后在SCI索引期刊及专业核心期刊发表论文共计200余篇,近5年发表SCI论文如下:
1. Wang L, Wei Y, Xue L, Guo QH, Liu W. Dignity and its influencing factors
in patients with cancer in North China: a cross-sectional study. Curr Oncol.
2019 Apr;26(2):188-193. (IF: 2.257)通讯作者
2. Fan HY, Zhang M, Liu W. Hypermethylated KCNQ1 acts as a tumor suppressor
in hepatocellular carcinoma. Biochemical and Biophysical Research
Communications. 2018 Sep;503(4):3100-3107. (IF: 2.559)通讯作者
3. Xu Z, Yao T, Liu W.miR-378a-3p sensitizes ovarian cancer cells to
cisplatin through targeting MAPK1/GRB2. Biomedicine &
Pharmacotherapy.107(2018)1410-1417. (IF:3.457)通讯作者
4. Wang N, Liu W. Increased expression of miR-552 acts as a potential
predictor biomarker for poor prognosis of colorectal cancer. Eur Rev Med
Pharmacol Sci. 2018 Jan;22(2):412-416. (IF: 2.387)通讯作者:
5. Ai N, Liu W, Li ZG, Ji H, Li B, Yang G. High expression of GP73 in primary
hepatocellular carcinoma and its function in the assessment of transcatheter
arterial chemoembolization. Oncol Lett. 2017 ;14(4):3953-3958. (IF:1.664)
通讯作者
6. Hu WX, jin PL, Liu W. Periostin Contributes to Cisplatin Resistance in
Human Non-small Cell Lung Cancer A549 Cells via Activation of Stat3 and Akt and
Upregulation of Survivin. Cellular Physiology and Biochemistry, 2016,
38(3):1199-1208. (IF:4.652) 通讯作者
7. Gao HX, Yan L, Li C, Zhao LM, Liu W. miR-200c regulates
crizotinib-resistant ALK-positive lung cancer cells by reversing
epithelial-mesenchymal transition via targeting ZEB1. Mol Med Rep.
2016;14(5):4135-4143.(IF:1.559)通讯作者
8. Zhao M, Zhang H, Zhu G, Liang J, Chen N, Yang Y, Liang X, Cai H, Liu W.
Association between overexpression of Wip1 and prognosis of patients with
nonsmall cell lung cancer. Oncol Lett. 2016;11(4): 2365–2370.(IF:1.482)通讯作者
9. Zhou X, Wang Y, Shan B, Han J, Zhu H, Lv Y, Fan X, Sang N, Liu X, Liu
W.The downregulation of miR-200c/141 promotes ZEB1/2 expression and gastric
cancer progression. Med Oncol. 2015;32(1):428-428.(IF:2.634)通讯作者
10. Jia L, Du Y, Li T, Lv Y, Wang Y, Zhang Y, Zhou X, Liu W. Differential
expression of vascular endothelial growth factor-A, -C and -D for the diagnosis
and prognosis of cancer patients with malignant effusions. Oncol Lett.
2015;10(2):667-674.(IF:1.554)通讯作者
11. Wang Y, Zhou X, Shan B, Han J, Wang F, Fan X, Lv Y, Chang L, Liu W.
Downregulation of microRNA 33a promotes cyclin dependent kinase 6, cyclin D1 and
PIM1 expression and gastric cancer cell proliferation. Mol
MedRep.2015;12(5):6491-6500.(IF:1.554)通讯作者
12. Wang N, Li Y, Zhou RM, Wang GY, Wang CM, Chen ZF, Liu W. Hsa-miR-196a2
functional SNP is associated with the risk of ESCC in individuals under 60 years
old. Biomarkers. 2014;19(1):43-48. (IF:2.260)通讯作者
13. Chang L, Guo FJ, Wang Y, Lv YL, Huo BJ, Wang L, Liu W. MicroRNA-200c
regulates the sensitivity of chemotherapy of gastric cancer SGC7901/DDP cells by
directly targeting RhoE. Pathol Oncol Res. 2014;20(1):93-98.(IF:1.855)通讯作者
14. Zuo J, Wang DH, Zhang YJ, Liu L, Liu FL, Liu W. Expression and mechanism
of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial
cells. Oncol Rep. 2013;30(4):1823-1831. (IF:2.868)通讯作者
15. Wang N, Li Y, Zhu LJ, Zhou RM, Jin W, Guo XQ, Wang CM, Chen ZF, Liu W. A
functional polymorphism rs11614913 in microRNA-196a2 is associated with an
increased risk of colorectal cancer although not with tumor stage and grade.
Biomed Rep. 2013; 1(5):737-742. (IF:2.98)通讯作者
16. Chang L, Guo F, Lv Y, Wang Y, Huo B, Wang L, Liu W. The inhibitory
effects of Endostar combined with chemotherapy on human Esophageal squamous cell
carcinoma xenograft in mice. Mol Biol Rep. 2013;40(1):669-673.(IF:1.958)通讯作者
17. Chen Y, Sun Y, Chen L, Xu X, Zhang X, Wang B, Min L, Liu W. miRNA-200c
increases the sensitivity of breast cancer cells to doxorubicin through the
suppression of E-cadherin-mediated PTEN/Akt signaling. Mol Med
Rep.2013;7(5):1579-1584. (IF:1.484)通讯作者