北京大学肿瘤医院

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胃肠肿瘤中心二病区 - 范彪

范彪简介

北京大学肿瘤医院胃肠肿瘤中心二病区主治医师、教学秘书、外科教研室秘书。师从国际胃癌协会主席、中国著名肿瘤学专家季加孚教授。2010-2012年至美国加州大学旧金山分校(UCSF)医学中心进行胃癌等消化系统肿瘤发病机制研究,参加其附属Benioff医院的病案讨论及临床观摩。2013年获得北京大学肿瘤学博士学位。工作后,2013.09-2015.08在北京大学第一医院外科培训基地参加北京市专科医师规范化培训。2015.09-2018.09在北京肿瘤医院参加胃肠肿瘤亚专科医师规范化培训并以优异成绩通过培训测试。目前主要从事胃肠道肿瘤的外科诊治,开展胃肠道肿瘤的根治手术、腹腔镜微创手术、注重患者神经功能保护和快速康复。在临床实践的基础上,同时还进行胃肠肿瘤的基础及临床研究。主持/参与多项国家级研究项目,如国家自然科学基金重大研究计划、国家自然科学基金面上项目、国自然青年科学基金等。作为第一作者/并列第一作者国际及国内期刊发表多篇学术成果。曾受邀在美国UCSF癌症中心学术会议、第10、11届国际胃癌学术会议、第13届全国胃癌会议进行会议发言。获北京大学2011-2012年度创新奖、第十届国际胃癌会议最佳口头报告奖、第88届日本胃癌学术年会青年学者奖。

发表论文

代表性论文:

1、Huangfu L#, Fan B#, Wang G, Gan X, Tian S, He Q, Yao Q, Shi J, Li X, Du H, Gao X, Xing X, Ji J. Novel prognostic marker LINC00205 promotes tumorigenesis and metastasis by competitively suppressing miRNA-26a in gastric cancer. Cell Death Discov. 2022 Jan 10;8(1):5.

2、Fan B, Ji K, Bu Z, Zhang J, Yang H, Li J, Wu X. ARHGAP11A Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer. Front Mol Biosci. 2021 Oct 18;8:720645.

3、Lu X, Peng B, Chen G, Pes MG, Ribback S, Ament C, Xu H, Pal R, Rodrigues PM, Banales JM, Evert M, Calvisi DF, Chen X, Fan B*, Wang J*. YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice. Am J Pathol. 2021 Sep;191(9):1651-1667.

4、Fan B, Bu Z, Zhang J, Zong X, Ji X, Fu T, Jia Z, Zhang Y, Wu X. Phase II trial of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer after curative surgery. BMC Cancer. 2021 Mar 2;21(1):216.

5、Hu X#, Chen L#, Du Y#, Fan B#, et al. Postoperative Chemotherapy With S-1 Plus Oxaliplatin Versus S-1 Alone in Locally Advanced Gastric Cancer (RESCUE-GC Study): A Protocol for a Phase III Randomized Controlled Trial. Chin J Cancer Res. 2017 Apr;29(2):144-148.

6、Li L#, Wen XZ#, Bu ZD, Cheng XJ, Xing XF, Wang XH, Zhang LH, Guo T, Du H, Hu Y, Fan B*, Ji JF*.Paclitaxel enhances tumoricidal potential of TRAIL via inhibition of MAPK in resistant gastric cancer cells. Oncol Rep. 2016 May;35(5):3009-17.

7、Li Z#, Fan B#, Shan F#, Tang L, Bu Z, Wu A, Zhang L, Wu X, Zong X, Li S, Ren H, Ji J. Gastrectomy in comprehensive treatment of advanced gastric cancer with synchronous liver metastasis: a prospectively comparative study. World J Surg Oncol. 2015 Jul 1;13:212.

8、Fan B#, Zhang LH#, Jia YN, Zhong XY, Liu YQ, Cheng XJ, Wang XH, Xing XF, Hu Y, Li YA, Du H, Zhao W, Niu ZJ, Lu AP, Li JY, Ji JF. Presence of S100A9-positive inflammatory cells in cancer tissues correlates with an early stage cancer and a better prognosis in patients with gastric cancer. BMC Cancer. 2012 Jul 28;12:316.

9、Fan B#, Malato Y#, Calvisi DF#, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H. Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest. 2012 Aug;122(8):2911-5.

10、Fan B#, Dachrut S#, Coral H, Yuen ST, Chu KM, Law S, Zhang L, Ji J*, Leung SY*, Chen X*. Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer. PLoS One. 2012;7(4):e29824.

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