副主任医师，博士毕业于中国医学科学院北京协和医院，2007年开始病理诊断工作，美国哈佛大学麻省总医院博士后，擅长消化、乳腺肿瘤等的病理诊断及病因机制研究。参与乳腺癌国家自然科学基金面上项目、胃癌及肠癌首都卫生发展科研专项、青年职工创新工作室等，主持北京大学医学青年培育基金胰腺癌项目，2019年美加病理年会“中国胃癌患者EBV病毒感染状态、微卫星不稳定、Her-2及PD-L1表达分析”获最佳摘要奖。北大肿瘤医院带教老师，参与《阿克曼外科病理学》英文翻译工作。 

代表性论著：

1、 F.Hu#, Y. Li#, L.Zhang#, D.Ji, X.Liu, Y.Chen, L. Wang and A. Wu*.Single-cell profiling reveals differences between human classical adenocarcinoma and mucinous adenocarcinoma. COMMUN BIOL.2023.

2、 Y. Li# , C. Pan#, Y. Gao# , L. Zhang , D. Ji , X. Cui , X. Zhang , Y. Cai , Y. Zhang , D.Wu , Z. Gao , Y. Sun , Z. Li , H. Luo* , A. Wu *. Total Neoadjuvant Therapy With PD-1 Blockade for High-Risk Proficient Mismatch Repair Rectal Cancer. JAMA Surg. 2024.

3、 L.Zhang#, Y.Wang#, Z Li#, D. Lin, Y. Liu, L. Zhou, D. Wang, A. Wu* and Z. Li*. Clinicopathological features of tumor mutation burden, Epstein-Barr virus infection, microsatellite instability and PD-L1 status in Chinese patients with gastric cancer. Diagnostic Pathology. 2021.

4、 Y. Chen#, D. Wang#, Y. Li#, L. Qi, W. Si, Y. Bo, X.Chen, Z. Ye, H. Fan, B. Liu, C. Liu, L. Zhang, X. Zhang, Z. Li, L. Zhu, A. Wu* and Z. Zhang*. Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer. Cancer Cell. 2024.

5、 Z.Liu#, Y.Wang#, L. Zhang#, Y. Jia, S. Fei, X.Ying, Y. Zhang, S. Li, Y. Sun, Z. Li, J. Ji*. Comparison of tumor regression grading systems for locally advanced gastric adenocarcinoma after neoadjuvant chemotherapy. WJGO.2021.