2018年主要论文
1. Zhiming Li, Yinglu Li, Ming Tang, Bin Peng, Xiaopeng Lu, Qiaoyan Yang, Qian Zhu, Tianyun Hou, Meiting Li, Chaohua Liu,Lina Wang, Xingzhi Xu, Ying Zhao, Haiying Wang, Yang Yang and Wei-Guo Zhu*. Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair. Cell Research. 2018;28(7):756-770.
2. Sai Ge, Xia Xia, Chen Ding, Bei Zhen, Quan Zhou, Jinwen Feng, Jiajia Yuan, Rui Chen, Yumei Li, Zhongqi Ge, Jiafu Ji, Lianhai Zhang, Jiayuan Wang, Zhongwu Li, Yumei Lai, Ying Hu, Yanyan Li, Yilin Li, Jing Gao, Lin Chen, Jianming Xu, Chunchao Zhang, Sung Yun Jung, Jong Min Choi, Antrix Jain, Mingwei Liu, Lei Song, Wanlin Liu, Gaigai Guo, Tongqing Gong, Yin Huang, Yang Qiu, Wenwen Huang, Tieliu Shi, Weimin Zhu, Yi Wang, Fuchu He, Lin Shen & Jun Qin. A proteomic landscape of diffuse-type gastric. Nature Communications. 2018;9:1012.
3. Xiaofeng Liu, Shiying Cai, Chunfeng Zhang, Zhenzhen Liu, Jianyuan Luo, Baocai Xing,* and Xiaojuan Du. Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress. Nucleic Acids Research. 2018:46(18):9601-9616.
4. Yinglu Li, Zhiming L, Liping Dong, Ming Tang, Ping Zhang, Chaohua Zhang, Ziyang Cao, Qian Zhu, Yongcan Chen, Hui Wang, Tianzhuo Wang, Danyu Lv, Lina Wang, Ying Zhao, Yang Yang, Haiying Wang, Hongquan Zhang, Robert G. Roederand Wei-Guo Zhu*. Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage. Nucleic Acids Research. 2018;46(15):7716-7730.
5. Dengbo Ji, HaizhaoYi, Dakui Zhang, Tiancheng Zhan, Zhaowei Li, Ming Li, Jinying Jia, Meng Qiao, Jinhong Xia, Zhiwei Zhai, Can Song and Jin Gu*. Somatic Mutations and Immune Alternation in Rectal Cancer Following Neoadjuvant Chemoradiotherapy. Cancer Immunology Research. 2018;6(11):1401-1416.
6. Jianhao Lai, Dehua Lu, Chenran Zhang, Hua Zhu, Liquan Gao, Yanpu Wang, Rui Bao, Yang Zhao, Bing Jia, Fan Wang, Zhi Yang*, Zhaofei Liu. Noninvasive small-animal imaging of galectin-1 upregulation for predicting tumor resistance to radiotherapy. Biomaterials. 2018;158:1-9.
7. Junnan Feng, Chuanke Zhao*, Lixin Wang, Like Qu, Hua Zhu, Zhi Yang, Guo An, Huifang Tian, and Chengchao Shou*. Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy. Theranostics. 2018;8(8):2094-2106.
8. Xiao-Yan Zhang, Shuai Wang, Xiao-Ting Li, Ying-Ping Wang, Yan-Jie Shi,Lin Wang, Ai-Wen Wu, Ying-Shi Sun*. MRI of Extramural Venous Invasion in Locally Advanced Rectal Cancer: Relationship to Tumor Recurrence and Overall Survival. Radiology. 2018;289(3):677-685.
9. Cong Fan, Juan Zhang, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin and Yuntao Xie*. RAD50 germline mutations are associated with poor survival in BRCA1/2-negative breast cancer patients. International Journal of Cancer. 2018;143(8):1935-1942.
10. The mTOR kinase inhibitor everolimus synergistically enhances the anti-tumor effect of the Bruton's tyrosine kinase (BTK) inhibitor PLS-123 on Mantle cell lymphoma. International Journal of Cancer. 2018;142(1):202-213.
11. Cunzhen Shi, Xiangqun Li, Xiaogan Wang, Ning Ding, Lingyan Ping, Yunfei Shi, Lan Mi, Yumei Lai, Yuqin Song1* and Jun Zhu*. The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma. Journal of Hematology & Oncology. 2018;11:43.
12. Xu Liang, Adrien Briaux, Véronique Becette, Camille Benoist, Anais Boulai, Walid Chemlali, Anne Schnitzler, Sylvain Baulande, Sofia Rivera, Marie-Ange Mouret-Reynier, Laurence Venat Bouvet, Thibaut De La Motte Rouge, Jérôme Lemonnier, Florence Lerebours and Céline Callens. Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609). Journal of Hematology & Oncology. 2018;11:124.
13. Zhentao Liu, Zuhua Chen, Jingyuan Wang, Mengqi Zhang, Zhongwu Li, Shubin Wang, Bin Dong, Cheng Zhang, Jing Gao* and Lin Shen*. Mouse avatar models of esophageal squamous cell carcinoma proved the potential for EGFR-TKI afatinib and uncovered Src family kinases involved in acquired resistance. J ournal of Hematology & Oncology. 2018;11:109.
14. Zuhua Chen, Wenwen Huang, Tiantian Tian, Wanchun Zang, Jingyuan Wang, Zhentao Liu, Zhongwu Li, Yumei Lai, Zhi Jiang, Jing Gao* and Lin Shen*. Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer. J ournal of Hematology & Oncology 2018;11:20.
15. Junya Yan, Xiaowen Wu, Jiayi Yu, Huan Yu, Tianxiao Xu, Kevin M. Brown, Xue Bai, Jie Daa, Meng Ma a, Huan Tang, Lu Si, Zhihong Chi, Xinan Sheng, Chuanliang Cui, Yan Kong*, Jun Guo*. Analysis of NRAS gain in 657 patients with melanoma and evaluation of its sensitivity to a MEK inhibitor. European Journal of Cancer. 2018;89:90-101.
16. Jingyi Zhang, Pengwei Ren, Da Xu, Xiaofeng Liu, Zhenzhen Liu, Chunfeng Zhang, Yuan Li, Lijun Wang, Xiaojuan Du, Baocai Xing∗. Human UTP14a promotes colorectal cancer progression by forming a positive regulation loop with c-Myc. Cancer Letters. 2018;440:106-115.
17. Jingyuan Wang, Zhentao Liu, Ziqi Wang, Shubin Wang, Zuhua Chen, Zhongwu Li Mengqi Zhang, Jianling Zou, Bin Dong, Jing Gao*, Lin Shen*. Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma. Cancer Letters. 2018;419:64-74.
18. Ying Liu, Yue-Hang Geng, Hui Yang, Han Yang, Yan-Ting Zhou, Hong-Quan Zhang, Xin-Xia Tian∗, Wei-Gang Fang∗. Extracellular ATP drives breast cancer cell migration and metastasis via S100A4 production by cancer cells and fibroblasts. Cancer Letters. 2018;430:1-10.
19. Xiaoxia Xu, Hua Zhu, Fei Liu, Yan Zhang, Jianhua Yang, Lifang Zhang, Lin Zhu, Nan Li, Hank F. Kung and Zhi Yang *. Imaging Brain Metastasis Patients With 18F-(2S,4R)-4-Fluoroglutamine. Clinical Nuclear Medicine. 2018;43(11):e392-e399.
20. Jialong Liang, Wanshi Cai, Dongdong Feng, Huajing Teng, Fengbiao Mao, Yi Jiang, Shanshan Hu, Xianfeng Li, Yujie Zhang, Baoguo Liu* and Zhong Sheng Sun*. Genetic landscape of papillary thyroid carcinoma in the Chinese population. Journal of Pathology. 2018;244(2):215-226.
21. Fan Wu1, Pin Gao, Wei Wu, Zaozao Wang, Jie Yang, Jiabo Di, Beihai Jiang* and Xiangqian Su*. STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer. Journal of Experimental & Clinical Cancer Research. 2018;37:144.
22. Xiaoting Lin, Dongshao Chen, Cheng Zhang, Xiaotian Zhang, Zhongwu Li, Bin Dong, Jing Gao*and Lin Shen*. Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint. Journal of Experimental & Clinical Cancer Research. 2018;37:129.
23. Dengbo Ji , Meng Qiao , Yunfeng Yao , Ming Li, Hailong Chen, Qi Dong, Jinying Jia, Xinxin Cui, Zhaowei Li, Jinhong Xia, Jin Gu*. Serum-based microRNA signature predicts relapse and therapeutic. EBioMedicine. 2018;35:189-19.
24. Xu Liang, Sophie Vacher, Anais Boulai, Virginie Bernard, Sylvain Baulande, Mylene Bohec, Ivan Bièche, Florence Lerebours and Céline Callens. Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer. Breast Cancer Research. 2018;20;88.
25. Chen Yang, Li Sun, Lingxin Zhang, Lixin Zhou, Ming Zhao, Yan Peng, Dongfeng Niu, Zhongwu Li, Xiaozheng Huang, Qiang Kang, Lin Jia, Jinping Lai and Dengfeng Cao. Diagnostic Utility of SATB2 in Metastatic Krukenberg Tumors of the Ovary An Immunohistochemical Study of 70 Cases With Comparison to CDX2, CK7, CK20, Chromogranin, and Synaptophysin. American Journal of Surgical. 2018;42(2):160-171.
26. Jianling Zou, Shuang Li, Zuhua Chen, Zhihao Lu, Jing Gao, Jianyin Zou, Xiaoting Lin, Yanyan Li Cheng Zhang* and Lin Shen*. A novel oral camptothecin analog, gimatecan, exhibits superior antitumor efficacy than irinotecan toward esophageal squamous cell carcinoma in vitro and in vivo. Cell Death & Disease. 2018;9:661.
27. Dongshao Chen, Xiaoting Lin, Cheng Zhang, Zhentao Liu, Zuhua Chen, Zhongwu Li, Jingyuan Wang, Beifang Li, Yanting Hu, Bin Dong, Lin Shen, Jiafu Ji, Jing Gao* and Xiaotian Zhang*. Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway. Cell Death & Disease. 2018;9:123.
28. Xiaofang Xing, Jianping Guo, Guangyu Ding, Bo Li, Bin Dong, Qin Feng, Shen Li, Jian Zhang, Xiaomin Ying, Xiaojing Cheng, Ting Guo, Hong Du, Ying Hu, Tao Zhou, Xiaohong Wang, Lin Li, Qingda Li, Meng Xie, Liting Li, Xiangyu Gao, Fei Shan, Ziyu Li, Shuqin Jia, Xianzi Wen, Jiping Wang & Jiafu Ji*. Analysis of PD1, PDL1, PDL2 expression and T cells infiltration in 1014 gastric cancer patients. OncoImmunology. 2018;7(3):e1356144.
29. Yue Meng, Lu Wang, Jianjun Xu and Qingyun Zhang*. AP4 positively regulates LAPTM4B to promote hepatocellular carcinoma growth and metastasis, whilst reducing chemotherapy sensitivity. Molecular Oncology. 2018;12(3):373-390.
30. Chaoting Zhang, Heyilimu Palashati, Qin Tan, Wenjing Ku, Yu Miao, Hongchao Xiong* and Zheming Lu*. Immediate and substantial evolution of T cell repertoire in peripheral blood and tumor microenvironment of patients with esophageal squamous cell carcinoma treated with preoperative chemotherapy. Carcinogenesis. 2018;39(11):1389-1398.
31. Jing Zhang, Song Wang, Zhiting Deng, Li Li, Guanghong Tan, Xin Liu, Hairong Zheng and Fei Yan. Ultrasound-Triggered Drug Delivery for Breast Tumor Therapy Through iRGD-Targeted Paclitaxel-Loaded Liposome-Microbubble Complexes. Journal of Biomedical Nanotechnology. 2018;14(8D):1384-1395.
32. Xin Ji, Zhao‑De Bu, Yan Yan, Zi‑Yu Li, Ai‑Wen Wu, Lian‑Hai Zhang, Ji Zhang, Xiao‑Jiang Wu, Xiang‑Long Zong, Shuang‑Xi Li, Fei Shan, Zi‑Yu Jia, Jia‑Fu Ji*. The 8th edition of the American Joint Committee on Cancer tumor-node-metastasis staging system for gastric cancer is superior to the 7th edition: results from a Chinese mono-institutional study of 1663 patients. Gastric Cancer. 2018;21(4):643-652.
33. Ziyu Li, Yinkui Wang, Fei Shan, Xiangji, Ying, Zhouqiao Wu, Kan Xue, Rulin Miao, Yan Zhang & Jiafu Ji*. ypTNM staging after neoadjuvant chemotherapy in the Chinese gastric cancer population: an evaluation on the prognostic value of the AJCC eighth edition cancer staging system. Gastric Cancer. 201821(6)::977-987.