研究专利
发明专利授权1. 陆哲明等，靶向TRBC1 CAR-T细胞的制备方法与应用，ZL2020106666952，20202. 李萍萍，一种治疗化疗药物引起的静脉炎的中药制剂及其制备方法，ZL2017111746207，20203. 陆哲明等，一种同时表达靶向CD19和CD20的CAR与PD1-CD28嵌合受体的慢病毒载体，ZL2017112885118，20204. 沈琳等，用于胃癌治疗的CDK4/6抑制剂联合HER2抑制剂的组合，ZL2018113384493，20205. 韩淑燕等，蒲公英提取物在制备抗癌药物中的应用，ZL20171…
2021-08-27研究成果
名称年度类型等级完成人肺癌化疗和靶向治疗疗效和预后相关的分子标志物2010年高等学校科学研究优秀成果奖科学技术进步奖二等奖王洁P53基因治疗的基础和临床研究2010年北京市科学技术奖三等奖张珊文肺癌化疗和靶向治疗疗效和预后相关的分子标志物研究2010年北京市科学技术奖三等奖王洁肺癌化疗和靶向治疗疗效和预后相关的分子标志物研究2011年中华医学科技奖三等奖王洁肺癌化疗和靶向治疗疗效和预后相关的分子标志物2011年华夏医学…
2021-08-272020年主要论文
1. Lu, Z., Zou, J., Li, S., Topper, M. J., Tao, Y., Zhang, H., Jiao, X., Xie, W., Kong, X., Vaz, M., Li, H., Cai, Y., Xia, L., Huang, P., Rodgers, K., Lee, B., Riemer, J. B., Day, C. P., Yen, R. C., Cui, Y., Brock, M. V. Epigenetic therapy inhibits metastases by disrupting premetastatic niches. Nature, 579(7798), 284–290. https://doi.org/10.1038/s41586-020-2054-x2. Xu J, Shen L, Zhou Z, Li J, …
2021-08-272019年主要论文
1. Yu J, Huang C, Sun Y, Su X, Cao H, Hu J, Wang K, Suo J, Tao K, He X, Wei H, Ying M, Hu W, Du X, Hu Y, Liu H, Zheng C, Li P, Xie J, Liu F, Li Z, Zhao G, Yang K, Liu C, Li H, Chen P, Ji J*, Li G; Chinese Laparoscopic Gastrointestinal Surgery Study (CLASS) Group. Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer:…
2021-08-272018年主要论文
1. Zhiming Li, Yinglu Li, Ming Tang, Bin Peng, Xiaopeng Lu, Qiaoyan Yang, Qian Zhu, Tianyun Hou, Meiting Li, Chaohua Liu,Lina Wang, Xingzhi Xu, Ying Zhao, Haiying Wang, Yang Yang and Wei-Guo Zhu*. Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair. Cell Research. 2018;28(7):756-770.2. Sai Ge, Xia Xia, Chen Ding, Bei Zhen, Quan Zhou, Jinwen Feng, Jiajia…
2021-08-272017年主要论文
1. Weizhi Xu, Junhu Wan, Jun Zhan, Xueying Li, Huiying He, Zhaomei Shi, Hongquan Zhang. Global profiling of crotonylation on non-histone proteins. Cell Res. 2017;27(7):946-949. (IF=15.606)2. Ming Ma, Fengfeng Zhuang, Xiongbing Hu, Bolun Wang, Xian-Zi Wen, Jia-Fu Ji, Jianzhong Jeff Xi. Efficient generation of mice carrying homozygous double-floxp alleles using the Cas9-Avidin/Biotin-donor DNA s…
2018-05-072016年主要论文
1. Zong L, Abe M, Seto Y, Ji J. The challenge of screening for early gastric cancer in China. Lancet. 2016;388(10060):2606.(IF=44.002)2. Yu Zhang ，Di Zhang ，Qian Li，Jing Liang，Luyang Sun，Xia Yi，ZheChen，Ruorong Yan，Guojia Xie，Wanjin Li，Shumeng Liu，Bosen Xu，LeiLi，Jianguo Yang，Lin He，Yongfeng Shang，Nucleation of DNA repair factors byFOXA1 links DNA demethylation to transcriptional…
2018-05-072015年主要论文
1. Si W, Huang W, Zheng Y, Yang Y, Liu X, Shan L, Zhou X, Wang Y, Su D, Gao J, Yan R, Han X, Li W, He L, Shi L, Xuan C, Liang J, Sun L, Wang Y, Shang Y. Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis. Cancer Cell. 2015;27(6):822-36.（IF=23.523）2. Tejpar S, Shen L, Wang X, Schilsky RL. Integrating biomarkers…
2015-07-232014年主要论文
1. Wen-Qing Li, Jun-Ling Ma, Lian Zhang, Linda M. Brown, Ji-You Li, Lin Shen, Kai-Feng Pan, Wei-Dong Liu, Yuanreng Hu, Zhong-Xiang Han, Susan Crystal-Mansour, David Pee, William J. Blot, Joseph F. Fraumeni Jr, Wei-Cheng You, Mitchell H. Gail. Effects of Helicobacter pylori Treatment on Gastric Cancer Incidence and Mortality in Subgroups. J Natl Cancer Inst. 2014;106(7):dju0116. (IF=15.16)2. Xi…
2015-07-232013年主要论文
1. Shen L, Shan YS, Hu HM, Price TJ, Sirohi B, Yeh KH, Yang YH, Sano T, Yang HK, Zhang X, Park SR, Fujii M, Kang YK, Chen LT. Management of gastric cancer in Asia: resource stratified guidelines. Lancet Oncol. 2013;14(12):e535 47. (IF=25.18)2. Zhao W, Wang L, Han H, Jin K, Lin N, Guo T, Chen Y, Cheng H, Lu F, Fang W, Wang Y, Xing B, Zhang Z. 1B50 1, a mAb raised against recurrent tumor cells, …
2015-07-232012年主要论文
1. Ma JL, Zhang L, Brown LM, Li JY, Shen L, Pan KF, Liu WD, Hu Y, Han ZX, Crystal Mansour S, Pee D, Blot WJ, Fraumeni JF, You WC, Gail MH. Fifteen year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality. J Natl Cancer Inst. 2012;104(6):488 92. (IF=13.76)2. Jingyi Zhou, Wenjuan Liao, Jing Yang, Ke Ma, Xue Li, Yachen Wang, Donglai Wang, Lina …
2015-07-232011年主要论文
1. Guo J, Si L, Kong Y, Flaherty KT, Xu X, Zhu Y, Corless CL, Li L, Li H, Sheng X, Cui C, Chi Z, Li S, Han M, Mao L, Lin X, Du N, Zhang X, Li J, Wang B, Qin S. Phase II, open label, single arm trial of imatinib mesylate in patients with metastatic melanoma harboring c Kit mutation or amplification. J Clin Oncol. 2011;29(21):2904 9. (IF=18.97)2. Xiaohan Yang, Wenhua Yu, Lei Shi, Luyang Sun, Jin…
2015-07-232010年主要论文
1. Ying Zhao, Jing Yang, Wenjuan Liao, Xiangyu Liu, Hui Zhang, Shan Wang, Donglai Wang, Jingnan Feng, Li Yu and Wei-Guo Zhu. Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. Nature Cell Biology. 2010 Jul;12(7):665-75. (IF=19.53)2. Ying Zhao Lina Wang Jing Yang, Ping Zhang, Ke Ma, Jingyi Zhou, Wenjuan Liao and Wei-Guo Zhu. Anti-neoplastic activity of t…
2015-07-23
