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重点实验室

科学研究及主要成果

2012年主要论文

发表时间:2015-07-23

    1. Ma JL, Zhang L, Brown LM, Li JY, Shen L, Pan KF, Liu WD, Hu Y, Han ZX, CrystalMansour S, Pee D, Blot WJ, Fraumeni JF, You WC, Gail MH. Fifteenyear effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality. J Natl Cancer Inst. 2012;104(6):48892. (IF=13.76)

    2. Jingyi Zhou, Wenjuan Liao, Jing Yang, Ke Ma, Xue Li, Yachen Wang, Donglai Wang, Lina Wang, Yu Zhang, Yuxin Yin, Ying Zhao and Wei-Guo Zhu. FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway. Autophagy. 2012;8(12):1712-1723. (IF=12.04)

    3. Wong BC, Zhang L, Ma JL, Pan KF, Li JY, Shen L, Liu WD, Feng GS, Zhang XD, Li J, Lu AP, Xia HH, Lam S, You WC. Effects of selective COX2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions. Gut. 2012;61(6):8128. (IF=10.11)

    4. Qin L, Liu X, Sun Q, Fan Z, Xia D, Ding G, Ong HL, Adams D, Gahl WA, Zheng C, Qi S, Jin L, Zhang C, Gu L, He J, Deng D, Ambudkar IS, Wang S. Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane. Proc Natl Acad Sci U S A. 2012;109(33):134349. (IF=9.68)

    5. Fen Yang, Luyang Sun, Qian Li, Xiao Han, Liandi Lei, Hua Zhang, and Yongfeng Shang. SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities. EMBO J. 2012;31(1):110-123. (IF=9.21)

    6. Jingyi Zhou, Wenjuan Liao, Jing Yang, Ke Ma, Xue Li, Yachen Wang, Donglai Wang, Lina Wang, Yu Zhang, Yuxin Yin, Ying Zhaoand Wei-Guo Zhu. FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway. Autophagy. 2012;8(12):1712-1723. (IF=7.45)

    7. Tingting Li, Yipeng Du, Likun Wang, Lei Huang, Wenlin Li, Ming Lu, Xue gong Zhang, Wei-Guo Zhu. Characterization and prediction of lysine (K)-acetyl-transferase (KAT) specific acetylation sites. Mol Cell Proteomics. 2012;11:M111.011080. (IF=7.40)

    8. Yu Yu, Junzhou Wu, Yunling Wang, TingZhao, BoMa, Yuqing Liu, WeigangFang, Wei-Guo Zhu & Hongquan Zhang. Kindlin 2 forms a transcriptional complex with b-catenin and TCF4 to enhance Wnt signalling . EMBO Reports. 2012;13(8):750-8. (IF=7.36)

    9. Li Y, Jiang T, Zhang J, Zhang B, Yang W, You G, Xu K, Wu J, Luo C, Song SW. Elevated serum antibodies against insulinlike growth factorbinding protein2 allow detecting earlystage cancers: evidences from glioma and colorectal carcinoma studies. Ann Oncol. 2012;23(9):241522. (IF=6.43)

    10. Wang S, Zhang QY, Zhou RL. Relationship between LAPTM4B gene polymorphism and susceptibility of primary liver cancer. Ann Oncol. 2012;23(7):18649. (IF=6.43)

    11. Han HB, Gu J, Zuo HJ, Chen ZG, Zhao W, Li M, Ji DB, Lu YY, Zhang ZQ. Let7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer. J Pathol. 2012;226(3):54455. (IF=6.32)

    12. Zhang W, Zhang J, Hoadley K, Kushwaha D, Ramakrishnan V, Li S, Kang C, You Y, Jiang C, Song SW, Jiang T, Chen CC. miR181d: a predictive glioblastoma biomarker that downregulates MGMT expression. Neuro Oncol. 2012;14(6):7129. (IF=5.72)

    13. Zhixing Zheng, Lian Li, Xiangyu Liu, Donglai Wang, Bo Tu, Lina Wang, Haiying Wang, and Wei-Guo Zhu. 5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins. The FASEB Journal. 2012;26:449-459. (IF=5.71)

    14. Xu H, Jiang B, Meng L, Ren T, Zeng Y, Wu J, Qu L, Shou C. Nαacetyltransferase 10 protein inhibits apoptosis through RelA/p65regulated MCL1 expression. Carcinogenesis. 2012;33(6):1193202. (IF=5.70)

    15. Si L, Kong Y, Xu X, Flaherty KT, Sheng X, Cui C, Chi Z, Li S, Mao L, Guo J. Prevalence of BRAF V600E mutation in Chinese melanoma patients: large scale analysis of BRAF and NRAS mutations in a 432case cohort. Eur J Cancer. 2012;48(1):94100. (IF=5.54)

    16. Li J, Cai H, Xu Z, Wang Q, Hang D, Shen N, Liu M, Zhang C, Abliz A, Ke Y. Nine complete genome sequences of cutaneous human papillomavirus genotypes isolated from healthy skin of individuals living in rural He Nan province, China. J Virol. 2012;86(21):11936. (IF=5.40)

    17. Dandan Wang, Jing Liang, Yu Zhang, Bin Gui, Feng Wang, Xia Yi, Luyang Sun, Zhi Yao, and Yongfeng Shang. Steroid Receptor Coactivator-interacting Protein (SIP) Inhibits Caspase-independent Apoptosis by Preventing Apoptosis-inducing Factor (AIF) from Being Released from Mitochondria. J Biol Chem. 2012;287(16):12612-12621. (IF=4.77)

    18. Xia Yi, Mei Hong, Bin Gui, Zhe Chen, Lei Li, Guojia Xie, Jing Liang, Xiaocheng Wang, and Yongfeng Shang. RNA Processing and Modification Protein, Carbon Catabolite Repression 4 (Ccr4), Arrests the Cell Cycle through p21-dependent and p53-independent Pathway. J Biol Chem. 2012;287(25):21045-21057. (IF=4.65)

    19. Zhang J, Pei R, Pang Z, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y. Prevalence and characterization of BRCA1 and BRCA2 germline mutations in Chinese women with familial breast cancer. Breast Cancer Res Treat. 2012;132(2):4218. (IF=4.43)

    20. Zhang M, Xu Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y. Somatic mutations in the BRCA1 gene in Chinese women with sporadic breast cancer. Breast Cancer Res Treat. 2012;132(1):33540. (IF=4.43)

    21. Hui Wang, Yun-Tao Xie, Ji-Yuan Han, Yuan Ruan, Ai-Ping Song, Li-Yuan Zheng, Wei-Zao Zhang, Constantin Sajdik, Yan Li, Xin-Xia Tian, et al. Genetic polymorphisms in centrobin and Nek2 are associated with breast cancer susceptibility in a Chinese Han population. Breast Cancer Res Treat. 2012;136:241-251. (IF=4.43)

    22. Zhang B, Xiang S, Zhong Q, Yin Y, Gu L, Deng D. The p16specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors. Hum Gene Ther. 2012;23(10):107181. (IF=4.22)

    23. Bin Gui, Xiao Han, Yu Zhang, Jing Liang, Dandan Wang, Chenghao Xuan, Zhipeng Yu, Yongfeng Shang. Dimerization of ZIP promotes its transcriptional repressive function and biological activity. International Journal of Biochemistry & Cell Biology. 2012;44:886-895. (IF=4.15)

    24. Guo F, Liu Y, Wang X, He Z, Weiss NS, Madeleine MM, Liu F, Tian X, Song Y, Pan Y, Ning T, Yang H, Shi X, Lu C, Cai H, Ke Y. Human papillomavirus infection and esophageal squamous cell carcinoma: a casecontrol study. Cancer Epidemiol Biomarkers Prev. 2012;21(5):7805. (IF=4.12)

    25. Liu F, Guo F, Zhou Y, He Z, Tian X, Guo C, Ning T, Pan Y, Cai H, Ke Y. The Anyang Esophageal Cancer Cohort Study: study design, implementation of fieldwork, and use of computeraided survey system. PLoS One. 2012;7(2):e31602. (IF=4.09)

    26. Wu J, Zhang Y, Wang Y, Kong R, Hu L, Schuele R, Du X, Ke Y. Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits. PLoS One. 2012;7(2):e31692. (IF=4.09)

    27. Xie W, Feng Q, Su Y, Dong B, Wu J, Meng L, Qu L, Shou C. Transcriptional regulation of PES1 expression by cJun in colon cancer. PLoS One. 2012;7(7):e42253. (IF=4.09)

    28. Fan B, Dachrut S, Coral H, Yuen ST, Chu KM, Law S, Zhang L, Ji J, Leung SY, Chen X. Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer. PLoS One. 2012;7(4):e29824. (IF=4.09)

    29. Lu ZM, Zhou J, Wang X, Guan Z, Bai H, Liu ZJ, Su N, Pan K, Ji J, Deng D. Nucleosomes correlate with in vivo progression pattern of de novo methylation of p16 CpG islands in human gastric carcinogenesis. PLoS One. 2012;7(4):e35928. (IF=4.09)

    30. Han Y, Huang H, Xiao Z, Zhang W, Cao Y, Qu L, Shou C. Integrated analysis of gene expression profiles associated with response of platinum/paclitaxelbased treatment in epithelial ovarian cancer. PLoS One. 2012;7(12):e52745. (IF=4.09)

    31. Song MY, Pan KF, Su HJ, Zhang L, Ma JL, Li JY, Yuasa Y, Kang D, Kim YS, You WC. Identification of serum microRNAs as novel noninvasive biomarkers for early detection of gastric cancer. PLoS One. 2012;7(3):e33608. (IF=4.09)

    32. Sun M, Gao L, Liu Y, Zhao Y, Wang X, Pan Y, Ning T, Cai H, Yang H, Zhai W, Ke Y. Whole genome sequencing and evolutionary analysis of human papillomavirus type 16 in central China. PLoS One. 2012;7(5):e36577. (IF=4.09)

    33. Yan Liu, Bing-quan Wu, Hao-hao Zhong, Xin-xia Tian, Wei-gang Fang. Quantification of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase and Correlations with Telomerase Activity in Lung Cancer. PLoS One. 2012;7(6):e38868. (IF=4.09)

    34. Jun Zhan, Xiang Zhu, Yongqing Guo, Yunling Wang, Yuxiang Wang, Guangliang Qiang, Miaomiao Niu, Jinxia Hu, Juan Du, Zhilun Li, Jia Cui, BoMa, Weigang Fang, Hongquan Zhang. Opposite Role of Kindlin-1 and Kindlin-2 in Lung Cancers. PLoS One. 2012;7(11):e50313. (IF=4.09)

    35. Ji-Yuan Han, Hui Wang, Yun-Tao Xie, Yan Li, Li-Yuan Zheng, Yuan Ruan, Ai-Ping Song, XinXia Tian, Wei-Gang Fang. Association of Germline Variation in CCNE1 and CDK2 with Breast Cancer Risk, Progression and Survival among Chinese Han Women. PLoS ONE. 2012;7(11):e49296. (IF=4.09)

    36. Jin X, Ding H, Ding N, Fu Z, Song Y, Zhu J. Homozygous A polymorphism of the complement C1qA276 correlates with prolonged overall survival in patients with diffuse large B cell lymphoma treated with RCHOP. J Hematol Oncol. 2012;5:51. (IF=3.99)

    37. Tao Wang, Xuelian Pei, Jun Zhan, Jinxia Hu, Yu Yu, Hongquan Zhang. FERM-containing protein FRMD5 is a p120-catenin interacting protein that regulates tumor progression. FEBS Letters. 2012;586:3044-3050. (IF=3.54)

    38. Han SY, Zhao MB, Zhuang GB, Li PP. Marsdenia tenacissima extract restored gefitinib sensitivity in resistant nonsmall cell lung cancer cells. Lung Cancer. 2012;75(1):307. (IF=3.43)

    39. Su Y, Shen J, Gao L, Tian H, Tian Z, Qin W. Molecular interactions of rereleased proteins in electrophoresis of human erythrocytes. Electrophoresis. 2012;33(910):14025. (IF=3.30)

    40. Bo Gu and Wei-Guo Zhu. Surf the Post-translational Modification Network of p53 Regulation. International Journal of Biological Sciences. 2012;8(5):672-685. (IF=3.17)

    41. Li J, Gao J, Hong J, Shen L. Efficacy and safety of sunitinib in Chinese patients with imatinibresistant or intolerant gastrointestinal stromal tumors. Future Oncol. 2012;8(5):61724. (IF=3.17)

    42. Wang F, Wang S, Wang Z, Duan J, An T, Zhao J, Bai H, Wang J. Phosphorylated EGFR expression may predict outcome of EGFRTKIs therapy for the advanced NSCLC patients with wildtype EGFR. J Exp Clin Cancer Res. 2012;31:65. (IF=3.07)

    43. Fan B, Zhang LH, Jia YN, Zhong XY, Liu YQ, Cheng XJ, Wang XH, Xing XF, Hu Y, Li YA, Du H, Zhao W, Niu ZJ, Lu AP, Li JY, Ji JF. Presence of S100A9positive inflammatory cells in cancer tissues correlates with an early stage cancer and a better prognosis in patients with gastric cancer. BMC Cancer. 2012;12:316. (IF=3.01)

    44. Du Y, Liu Z, Gu L, Zhou J, Zhu BD, Ji J, Deng D. Characterization of human gastric carcinomarelated methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo. BMC Cancer. 2012;12:249. (IF=3.01)