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重点实验室

科学研究及主要成果

2013年主要论文

发表时间:2015-07-23

    1. Shen L, Shan YS, Hu HM, Price TJ, Sirohi B, Yeh KH, Yang YH, Sano T, Yang HK, Zhang X, Park SR, Fujii M, Kang YK, Chen LT. Management of gastric cancer in Asia: resourcestratified guidelines. Lancet Oncol. 2013;14(12):e53547. (IF=25.18)

    2. Zhao W, Wang L, Han H, Jin K, Lin N, Guo T, Chen Y, Cheng H, Lu F, Fang W, Wang Y, Xing B, Zhang Z. 1B501, a mAb raised against recurrent tumor cells, targets liver tumorinitiating cells by binding to the calcium channel α2δ1 subunit. Cancer Cell. 2013;23(4):54156. (IF=24.76)

    3. He XR, Wang Q, Han SY, Li PP. Corticosteroids for prevention of tuberculosis mortality. Lancet Infect Dis. 2013;13(11):916. (IF=19.97)

    4. Ying Zhao, Xue Li, Ke Ma, Jing Yang, Jingyi Zhou, Wan Fu, Fuzheng Wei, Lina Wang and Wei-Guo Zhu. The axis of MAPK1/3-XBP1u-FOXO1 controls autophagic dynamics in cancer cells. Autophagy. 2013;9(5):794-796. (IF=12.04)

    5. Ying Zhao, Xue Li, Mu-Yan Cai, Ke Ma, Jing Yang, Jingyi Zhou, Wan Fu, Fu-Zheng Wei, Lina Wang, Dan Xie, Wei-Guo Zhu. XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells. Cell Research. 2013;23(4):491-507. (IF=10.53)

    6. Ni X, Zhuo M, Su Z, Duan J, Gao Y, Wang Z, Zong C, Bai H, Chapman AR, Zhao J, Xu L, An T, Ma Q, Wang Y, Wu M, Sun Y, Wang S, Li Z, Yang X, Yong J, Su XD, Lu Y, Bai F, Xie XS, Wang J. Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients. Proc Natl Acad Sci U S A. 2013;110(52):210838. (IF=9.74)

    7. Donglai Wang, Jingyi Zhou, Xiangyu Liu, Danyu Lu, Changchun Shen, Yipeng Du, Fu-Zheng Wei, Boyan Song, Xiaopeng Lu, YuYu, Lina Wang, Ying Zhao, Haiying Wang, Yang Yang, Yoshimitsu Akiyama, Hongquan Zhang, and Wei-Guo Zhu. Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability. Proc Natl Acad Sci U S A. 2013;110(14):5516-5521. (IF=9.74)

    8. Xiaofan Wei, Yang Xia, Feng Li, Yan Tang, Jing Nie, Youhua Liu, Zhanmei Zhou, Hongquan Zhang, and Fan Fan Hou. Kindlin-2 Mediates Activation of TGF-β/Smad Signaling and Renal Fibrosis. J Am Soc Nephrol. 2013;24:1387-1398. (IF=8.99)

    9. Du L, Rao G, Wang H, Li B, Tian W, Cui J, He L, Laffin B, Tian X, Hao C, Liu H, Sun X, Zhu Y, Tang DG, Mehrpour M, Lu Y, Chen Q. CD44positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer. Cancer Res. 2013;73(8):268294. (IF=8.65)

    10. Rao G, Wang H, Li B, Huang L, Xue D, Wang X, Jin H, Wang J, Zhu Y, Lu Y, Du L, Chen Q. Reciprocal interactions between tumorassociated macrophages and CD44positive cancer cells via osteopontin/CD44 promote tumorigenicity in colorectal cancer. Clin Cancer Res. 2013;19(4):78597. (IF=7.84)

    11. Dai J, Kong Y, Si L, Chi Z, Cui C, Sheng X, Mao L, Li S, Lian B, Yang R, Liu S, Xu X, Guo J. Largescale analysis of PDGFRA mutations in melanomas and evaluation of their sensitivity to tyrosine kinase inhibitors imatinib and crenolanib. Clin Cancer Res. 2013;19(24):693542. (IF=7.84)

    12. Lian B, Si L, Cui C, Chi Z, Sheng X, Mao L, Li S, Kong Y, Tang B, Guo J. Phase II randomized trial comparing highdose IFNα2b with temozolomide plus cisplatin as systemic adjuvant therapy for resected mucosal melanoma. Clin Cancer Res. 2013;19(16):448898. (IF=7.84)

    13. Xu Y, Diao L, Chen Y, Liu Y, Wang C, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Deng D, Narod SA, Xie Y. Promoter methylation of BRCA1 in triplenegative breast cancer predicts sensitivity to adjuvant chemotherapy. Ann Oncol. 2013;24(6):1498505. (IF=7.38)

    14. Cui C, Mao L, Chi Z, Si L, Sheng X, Kong Y, Li S, Lian B, Gu K, Tao M, Song X, Lin T, Ren X, Qin S, Guo J. A phase II, randomized, doubleblind, placebocontrolled multicenter trial of Endostar in patients with metastatic melanoma. Mol Ther. 2013;21(7):145663. (IF=7.04)

    15. Yu Yu, Junzhou Wu, Lizhao Guan, Lihua Qi, Yan Tang, BoMa, Jun Zhan, Yunling Wang, Weigang Fangand Hongquan Zhang. Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the icroRNA200 gene family. International Journal of Cancer. 2013;133:1368-1380. (IF=6.20)

    16. He Z, Liu Y, Sun Y, Xi LF, Chen K, Zhao Y, Gao L, Liu F, Pan Y, Ning T, Zhang L, Cai H, Ke Y. Human papillomavirus genital infections among men, China, 20072009. Emerg Infect Dis. 2013;19(6):9925. (IF=6.0)

    17. Ji D, Li M, Zhan T, Yao Y, Shen J, Tian H, Zhang Z, Gu J. Prognostic role of serum AZGP1, PEDF and PRDX2 in colorectal cancer patients. Carcinogenesis. 2013;34(6): 126572. (IF=5.64)

    18. Wang Z, Zhang J, Wang Y, Xing R, Yi C, Zhu H, Chen X, Guo J, Guo W, Li W, Wu L, Lu Y, Liu S. Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases. Carcinogenesis. 2013;34(1):12838. (IF=5.64)

    19. Jin L, Qin L, Xia D, Liu X, Fan Z, Zhang C, Gu L, He J, Ambudkar IS, Deng D, Wang S. Active secretion and protective effect of salivary nitrate against stress in human volunteers and rats. Free Radic Biol Med. 2013;57:617. (IF=5.27)

    20. Zhang W, Zhang J, Yan W, You G, Bao Z, Li S, Kang C, Jiang C, You Y, Zhang Y, Chen CC, Song SW, Jiang T. Wholegenome microRNA expression profiling identifies a 5microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme. Cancer. 2013;119(4):81424. (IF=5.20)

    21. Li H, Wang J, Xu H, Xing R, Pan Y, Li W, Cui J, Zhang H, Lu Y. Decreased fructose1, 6bisphosphatase2 expression promotes glycolysis and growth in gastric cancer cells. Mol Cancer. 2013;12(1):110. (IF=5.13)

    22. W-H Li, Y Qiu, H-Q Zhang, Y Liu, J-F You, X-X Tian, and W-G Fang. P2Y2 receptor promotes cell invasion and metastasis in prostate cancer cells. British Journal of Cancer. 2013;109(6):1666-1675. (IF=5.08)

    23. Xiaohan Yang, Lei Li, Jing Liang, Lei Shi, Jianguo Yang, Xia Yi, Di Zhang, Xiao Han, NaYu, and Yongfeng Shang. Histone Acetyltransferase 1 Promotes Homologous Recombination in DNA Repair by Facilitating Histone Turnover. J Biol Chem. 2013;288(25):18271-18282. (IF=4.65)

    24. Lin N, Song Y, Zheng W, Tu M, Xie Y, Wang X, Ping L, Ying Z, Zhang C, Deng L, Liu W, Zhu J. A prospective phase II study of Lasparaginase CHOP plus radiation in newly diagnosed extranodal NK/Tcell lymphoma, nasal type. J Hematol Oncol. 2013;6(1):44. (IF=4.46)

    25. Lv J, Liu C, Huang H, Meng L, Jiang B, Cao Y, Zhou Z, She T, Qu L, Wei Song S, Shou C. Suppression of breast tumor growth by DNA vaccination against phosphatase of regenerating liver 3. Gene Ther. 2013;20(8):83445. (IF=4.32)

    26. Liu Y, Xing R, Zhang X, Dong W, Zhang J, Yan Z, Li W, Cui J, Lu Y. miR375 targets the p53 gene to regulate cellular response to ionizing radiation and etoposide in gastric cancer cells. DNA Repair (Amst). 2013;12(9):74150. (IF=4.27)

    27. Ting Zhao, Lizhao Guan, YuYu, Xuelian Pei, Jun Zhan, Ling Han, Yan Tang, Feng Li, Weigang Fang, Hongquan Zhang. Kindlin-2 promotes genome instability in breast cancer cells. Cancer Letters. 2013;330:208-216. (IF=4.26)

    28. untupalli SR, Cao D, Shroff R, Gao F, Menias C, Stewart Massad L, Powell MA, Mutch DG, Thaker PH. Wilms' tumor 1 protein and estrogen receptor beta expression are associated with poor outcomes in uterine carcinosarcoma. Ann Surg Oncol. 2013;20(7):23739. (IF=4.12)

    29. Si L, Guo J. Ckitmutated melanomas: the Chinese experience. Curr Opin Oncol. 2013;25(2):1605. (IF=4.03)

    30. Cao D. Thyroidlike follicular carcinoma of the kidney. J Urol. 2013;190 (1):2789. (IF=3.75)

    31. Wang Y, Sheng S, Zhang J, Dzinic S, Li S, Fang F, Wu N, Zheng Q, Yang Y. Elevated maspin expression is associated with better overall survival in esophageal squamous cell carcinoma (ESCC). PLoS One. 2013;8(5):e63581. (IF=3.73)

    32. Bai H, Wang Z, Wang Y, Zhuo M, Zhou Q, Duan J, Yang L, Wu M, An T, Zhao J, Wang J. Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced nonsmall cell lung cancer. PLoS One. 2013;8(2):e54170. (IF=3.73)

    33. Zhang M, Xu JJ, Zhou RL, Zhang QY. cAMP responsive element binding protein1 is a transcription factor of lysosomalassociated protein transmembrane4 Beta in human breast cancer cells. PLoS One. 2013;8(2):e57520. (IF=3.73)

    34. Song MY, Su HJ, Zhang L, Ma JL, Li JY, Pan KF, You WC. Genetic polymorphisms of miR146a and miR27a, H. pylori infection, and risk of gastric lesions in a Chinese population. PLoS One. 2013;8(4):e61250. (IF=3.73)

    35. Yang C, Gu L, Deng D. Bone marrowderived cells may not be the original cells for carcinogeninduced mouse gastrointestinal carcinomas. PLoS One. 2013;8(11): e79615. (IF=3.73)

    36. Chen D, Jiang B, Xing J, Liu M, Cui M, Liu Y, Wang Z, Chen L, Yang H, Zhang C, Yao Z, Zhang N, Ji J, Qu H, Su X. Validation of the memorial SloanKettering Cancer Center nomogram to predict diseasespecific survival after R0 resection in a Chinese gastric cancer population. PLoS One. 2013;8(10):e76041. (IF=3.73)

    37. Li J, Pan Y, Deng Q, Cai H, Ke Y. Identification and characterization of eleven novel human gammapapillomavirus isolates from healthy skin, found at low frequency in a normal population. PLoS One. 2013;8(10):e77116. (IF=3.73)

    38. Guo R, Li Y, Ning J, Sun D, Lin L, Liu X. HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor3 and affect immunomodulatory functions in human nonsmall cell lung cancer cells. PLoS One. 2013;8(4):e62729. (IF=3.73)

    39. Lv A, Li Z, Tian X, Guan X, Zhao M, Dong B, Hao C. SKP2 high expression, KIT exon 11 deletions, and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors. PLoS One. 2013;8(5):e62951. (IF=3.73)

    40. Wang S, An T, Duan J, Zhang L, Wu M, Zhou Q, Chen J, Zhuo M, Yang L, Wang Y, Bai H, Wang J. Alterations in EGFR and related genes following neoadjuvant chemotherapy in Chinese patients with nonsmall cell lung cancer. PLoS One. 2013;8(3):e51021. (IF=3.73)

    41. Li S, Zheng Q, Ma Y, Wang Y, Feng Y, Zhao B, Yang Y. Implications of false negative and false positive diagnosis in lymph node staging of NSCLC by means of 1?FFDG PET/CT. PLoS One. 2013;8(10):e78552. (IF=3.73)

    42. Yu Yu, Lihua Qi, Junzhou Wu, Yunling Wang, Weigang Fang, Hongquan Zhang. Kindlin 2 Regulates Myogenic Related Factor Myogenin via a Canonical Wnt Signaling in Myogenic Differentiation. PLoS ONE. 2013; 8(5):e63490. (IF=3.73)

    43. Song G, Wang X, Jia J, Yuan Y, Wan F, Zhou X, Yang H, Ren J, Gu J, Lyerly HK. Elevated level of peripheral CD8(+)CD28() T lymphocytes are an independent predictor of progressionfree survival in patients with metastatic breast cancer during the course of chemotherapy. Cancer Immunol Immunother. 2013;62(6):112330. (IF=3.64)

    44. Min L, Xu H, Wang J, Qu L, Jiang B, Zeng Y, Meng L, Jin H, Shou C. Nαacetyltransferase 10 protein is a negative regulator of 28S proteasome through interaction with PA28β. FEBS Lett. 2013;587(11):16307. (IF=3.58)

    45. Jianchao Gao, Ammad Aslam Khan, Takashi Shimokawa, Jun Zhan, Staffan Strömblad, Weigang Fang, Hongquan Zhang. A feedback regulation between Kindlin-2 and GLI1 in prostate cancer cells. FEBS Letters. 2013;587:631-638. (IF=3.58)

    46. Li N, Zhu H, Chu TW, Yang Z. Preparation and biological evaluation of ??mTcN4IPA for single photon emission computerized tomography imaging of hypoxia in mouse tumor. Eur J Med Chem. 2013;69:22331. (IF=3.50)

    47. Xing X, Lian S, Hu Y, Li Z, Zhang L, Wen X, Du H, Jia Y, Zheng Z, Meng L, Shou C, Ji J. Phosphatase of regenerating liver3 (PRL3) is associated with metastasis and poor prognosis in gastric carcinoma. J Transl Med. 2013;11:309. (IF=3.46)

    48. Yuanming Pan, Jiaqiang Huang, Rui Xing, Xin Yin, Jiantao Cui, Wenmei Li, Jun Yu, Youyong Lu. Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection. J Transl Med. 2013;11:173 (IF=3.46)

    49. Jin KM, Lu M, Liu FF, Gu J, Du XJ, Xing BC. NWASP is highly expressed in hepatocellular carcinoma and associated with poor prognosis. Surgery. 2013;153(4):51825. (IF=3.37)

    50. Zhang J, Leng JH, Qian HG, Qiu H, Wu JH, Liu BN, Li CP, Hao CY. En bloc pancreaticoduodenectomy and right colectomy in the treatment of locally advanced colon cancer. Dis Colon Rectum. 2013;56(7):87480. (IF=3.34)

    51. Zhan T, Gu J, Li M, Du C. Intermediatefraction neoadjuvant radiotherapy for rectal cancer. Dis Colon Rectum. 2013;56(4):42232. (IF=3.34)

    52. An J, Pan Y, Yan Z, Li W, Cui J, Yuan J, Tian L, Xing R, Lu Y. MiR23a in amplified 19p13.13 loci targets metallothionein 2A and promotes growth in gastric cancer cells. J Cell Biochem. 2013;114(9):21609. (IF=3.06)