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重点实验室

科学研究及主要成果

2015年主要论文

发表时间:2015-07-23

    1. Si W, Huang W, Zheng Y, Yang Y, Liu X, Shan L, Zhou X, Wang Y, Su D, Gao J, Yan R, Han X, Li W, He L, Shi L, Xuan C, Liang J, Sun L, Wang Y, Shang Y. Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis. Cancer Cell. 2015;27(6):822-36.(IF=23.523)

    2. Tejpar S, Shen L, Wang X, Schilsky RL. Integrating biomarkers in colorectal cancer trials in the West and China. Nat Rev Clin Oncol. 2015;12(9):553-60.(IF=14.18)

    3. Han H, Du Y, Zhao W, Li S, Chen D, Zhang J, Liu J, Suo Z, Bian X, Xing B, Zhang Z. PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells. Nat Commun. 2015;6:8271.(IF=11.47)

    4. Cui C, Gan Y, Gu L, Wilson J, Liu Z, Zhang B, Deng D. P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis. Genome Biology. 2015;16(1):252(IF=10.81)

    5. Yan R, He L, Li Z, Han X, Liang J, Si W, Chen Z, Li L, Xie G, Li W, Wang P, Lei L, Zhang H, Pei F, Cao D, Sun L, Shang Y. SCFJFK is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer. Genes Dev. 2015;29(6):672-85.(IF=10.798)

    6. Pan KF, Zhang L, Gerhard M, Ma JL, Liu WD, Ulm K, Wang JX, Zhang L, Zhang Y, Bajbouj M, Zhang LF, Li M, Vieth M, Liu RY, Quante M, Wang LH, Suchanek S, Zhou T, Guan WX, Schmid R, Classen M, You WC. A large randomised controlled intervention trial to prevent gastric cancer by eradication of Helicobacter pylori in Linqu County, China: baseline results and factors affecting the eradication. Gut pii: gutjnl-2015-309197. doi: 10.1136/gutjnl-2015-309197(IF=10.73)

    7. Wang Z, Shen Z, Li Z, Duan J, Fu S, Liu Z, Bai H, Zhang Z, Zhao J, Wang X, Wang J. Activation of the BMP-BMPR pathway conferred resistance to EGFR-TKIs in lung squamous cell carcinoma patients with EGFR mutations. Proc Natl Acad Sci U S A. 2015;112(32):9990-5.(IF=9.674)

    8. Wang Y, Liu C, Luo M, Zhang Z, Gong J, Li J, You L, Dong L, Su R, Lin H, Ma Y, Wang F, Wang Y, Chen J, Zhang J, Jia H, Kong Y, Yu J. Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer. Cancer Res. 2015;75(7):1332-44.(IF=9.329)

    9. Liu C, Li S, Dai X, Ma J, Wan J, Jiang H, Wang P, Liu Z, Zhang H. PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex. Nucleic Acids Res. 2015;43(13):6270-84.(IF=9.112)

    10. Wan J, Zhan J, Li S, Ma J, Xu W, Liu C, Xue X, Xie Y, Fang W, Chin YE, Zhang H. PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression. Nucleic Acids Res. 2015;43(7):3591-604.(IF=9.112)

    11. Yuan H, Chen J, Liu Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y. Association of PIK3CA Mutation Status before and after Neoadjuvant Chemotherapy with Response to Chemotherapy in Women with Breast Cancer. Clin Cancer Res. 2015;21(19):4365-72.(IF=8.722)

    12. Gao J, Li N, Dong Y, Li S, Xu L, Li X, Li Y, Li Z, Ng SS, Sung JJ, Shen L, Yu J. miR-34a-5p suppresses colorectal cancer metastasis and predicts recurrence in patients with stage II/III colorectal cancer. Oncogene. 2015;34(31):4142-52.(IF=8.459)

    13. Sun J, Wang Y, Xia Y, Xu Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Lou H, Xie Y. Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer. PLoS Genet. 2015;11(5):e1005228. (IF=7.528)

    14. Wang C, Zhang J, Wang Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y. Prevalence of BRCA1 mutations and responses to neoadjuvant chemotherapy among BRCA1 carriers and non-carriers with triple-negative breast cancer. Ann Oncol. 2015;26(3):523-8.(IF=7.04)

    15. Hongwei Liu, Xue-wei Liu, Guangying Dong, Jing Zhou, Yang Liu, Yan Gao, Xiao-yong Liu, Liankun Gu, Zheng Sun, Dajun Deng. P16 Methylation as an Early Predictor for Cancer Development from Oral Epithelial Dysplasia: A Double-Blind Multicentre Prospective Study. EBioMedicine 2015;2: doi: 10.1016/j.ebiom.2015.03.015

    16. Liu Y, Lu Z, Xu R, Ke Y. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget. 2015;7(5):5852-5864(6.359)

    17. Liu Y, Yang W, Pan Y, Ji J, Lu Z, Ke Y. Genome-wide analysis of Epstein-Barr virus (EBV) isolated from EBV-associated gastric carcinoma (EBVaGC). Oncotarget. 2015;7(4):4903-4914.(IF=6.359)

    18. Lu S, Yang Y, Du Y, Cao LL, Li M, Shen C, Hou T, Zhao Y, Wang H, Deng D, Wang L, He Q, Zhu WG. The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2. Oncotarget. 2015;6(33):34704-17.(IF=6.359)

    19. Deng L, Song Y, Young KH, Hu S, Ding N, Song W, Li X, Shi Y, Huang H, Liu W, Zheng W, Wang X, Xie Y, Lin N, Tu M, Ping L, Ying Z, Zhang C, Sun Y, Zhu J. Hepatitis B virus-associated diffuse large B-cell lymphoma: unique clinical features, poor outcome, and hepatitis B surface antigen-driven origin. Oncotarget. 2015;6(28):25061-73.(IF=6.359)

    20. He X, Li J, Guo W, Liu W, Yu J, Song W, Dong L, Wang F, Yu S, Zheng Y, Chen S, Kong Y, Liu C. Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma. Oncotarget. 2015;6(4):2302-14.(IF=6.359)

    21. Ding N, Li X, Shi Y, Ping L, Wu L, Fu K, Feng L, Zheng X, Song Y, Pan Z, Zhu J. Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma. Oncotarget. 2015;6(17):15122-36.(IF=6.359)

    22. Zhan J, Song J, Wang P, Chi X, Wang Y, Guo Y, Fang W, Zhang H. Kindlin-2 induced by TGF-β signaling promotes pancreatic ductal adenocarcinoma progression through downregulation of transcriptional factor HOXB9. Cancer Lett. 2015;361(1):75-85.(IF=5.621)

    23. Guo B, Gao J, Zhan J, Zhang H. Kindlin-2 interacts with and stabilizes EGFR and is required for EGF-induced breast cancer cell migration. Cancer Lett. 2015;361(2):271-81.(5.621)

    24. Yuan F, Qingfeng Z, Jia W, Chao L, Shi Y, Yuzhao W, Chao A, Yue Y. Influence of Metastatic Status and Number of Removed Lymph Nodes on Survival of Patients With Squamous Esophageal Carcinoma. Medicine. 2015;94(48):e1973.(IF=5.723)

    25. Liu F, Hang D, Deng Q, Liu M, Xi L, He Z, Zhang C, Sun M, Liu Y, Li J, Pan Y, Ning T, Guo C, Liang Y, Xu R, Zhang L, Cai H, Ke Y. Concurrence of oral and genital human papillomavirus infection in healthy men: a population-based cross-sectional study in rural China. Sci Rep. 2015;5:15637.(IF=5.578)

    26. Liu M, He Z, Zhang C, Liu F, Liu Y, Li J, Xu Z, Wang Q, Hang D, Shen N, Pan Y, Guo C, Cai H, Ke Y. Transmission of genital human papillomavirus infection in couples: a population-based cohort study in rural China. Sci Rep. 2015;5:10986.(IF=5.578)

    27. Wang Z, Li Z, Ding X, Shen Z, Liu Z, An T, Duan J, Zhong J, Wu M, Zhao J, Zhuo M, Wang Y, Wang S, Sun Y, Bai H, Wang J. ERβ localization influenced outcomes of EGFR-TKI treatment in NSCLC patients with EGFR mutations. Sci Rep. 2015;5:11392.(IF=5.578)

    28. Zhang L, Liu Y, Wang X, Tang Z, Li S, Hu Y, Zong X, Wu X, Bu Z, Wu A, Li Z, Li Z, Huang X, Jia L, Kang Q, Liu Y, Sutton D, Wang L, Luo L, Ji J. The extent of inflammatory infiltration in primary cancer tissues is associated with lymphomagenesis in immunodeficient mice. Sci Rep. 2015;5:9447.(IF=5.578)

    29. Zhu Y, Tian T, Li Z, Tang Z, Wang L, Wu J, Li Y, Dong B, Li Y, Li N, Zou J, Gao J, Shen L. Establishment and characterization of patient-derived tumor xenograft using gastroscopic biopsies in gastric cancer. Sci Rep. 2015;5:8542.(IF=5.578)

    30. Zhang Y, Pan KF, Zhang L, Ma JL, Zhou T, Li JY, Shen L, You WC. Helicobacter pylori, cyclooxygenase-2 and evolution of gastric lesions: results from an intervention trial in China. Carcinogenesis. 2015;36(12):1572-9.(IF=5.334)

    31. Shen C, Wang D, Liu X, Gu B, Du Y, Wei FZ, Cao LL, Song B, Lu X, Yang Q, Zhu Q, Hou T, Li M, Wang L, Wang H, Zhao Y, Yang Y, Zhu WG. SET7/9 regulates cancer cell proliferation by influencing β-catenin stability. FASEB J. 2015;29(10):4313-23.(IF=5.043)

    32. Ji J, Jia S, Jia Y, Ji K, Hargest R, Jiang WG. WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-γ pathways. Br J Cancer. 2015;113(6):921-33.(IF=4.836)

    33. Wang S, Su X, Bai H, Zhao J, Duan J, An T, Zhuo M, Wang Z, Wu M, Li Z, Zhu J, Wang J. Identification of plasma microRNA profiles for primary resistance to EGFR-TKIs in advanced non-small cell lung cancer (NSCLC) patients with EGFR activating mutation. J Hematol Oncol. 2015;8(1):127.(IF=4.812)

    34. Chenghua Cui, Zheming Lu, Liu Yang, Yanhong Gao, Liankun Gu, Chen Yang, Zhiqian Zhang, Baocai Xin, Dajun Deng, Zhongsheng Sun. Genome-wide identification of differential methylation between primary and recurrent hepatocellular carcinomas. Mol Carcinogenesis 2015, in press (IF=4.81)

    35. Wang Y, Zheng Z, Zhang J, Wang Y, Kong R, Liu J, Zhang Y, Deng H, Du X, Ke Y. A Novel Retinoblastoma Protein (RB) E3 Ubiquitin Ligase (NRBE3) Promotes RB Degradation and Is Transcriptionally Regulated by E2F1 Transcription Factor. J Biol Chem. 2015;290(47):28200-13.(IF=4.573)

    36. Zhou J, Peng Z, Liu Y, Gong J, Zhang X, Lu M, Gao J, Li Y, Li Y, Shen L. Predictive value of serum HER2 ECD in patients with HER2-positive advanced gastric cancer treated with trastuzumab plus chemotherapy. J Gastroenterol. 2015;50(9):955-61.(IF=4.523)

    37. Tan X, Wang H, Luo G, Ren S, Li W, Cui J, Gill HS, Fu SW, Lu Y. Clinical significance of a point mutation in DNA polymerase beta (POLB) gene in gastric cancer. Int J Biol Sci. 2015;11(2):144-55.(IF=4.509)

    38. She T, Qu L, Wang L, Yang X, Xu S, Feng J, Gao Y, Zhao C, Han Y, Cai S, Shou C. Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer Prev Res. 2015;8(5):464-74.(IF=4.44)

    39. Bai C, Yang M, Fan Z, Li S, Gao T, Fang Z. Associations of chemo- and radio-resistant phenotypes with the gap junction, adhesion and extracellular matrix in a three-dimensional culture model of soft sarcoma. J Exp Clin Cancer Res. 2015;34(1):58.(IF=4.429)

    40. Lan F, Yu H, Hu M, Xia T, Yue X. miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met. J Neurochem. 2015;135(2):274-86.(IF=4.281)

    41. Zhang Y, Wu H, Chen Z, Knisely JP, Nath R, Feng Z, Bao S, Deng J. Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy. Int J Radiat Oncol Biol Phys. 2015;93(3):523-31.(IF=4.258)

    42. He Y, Wang J, Wang J, Yung VY, Hsu E, Li A, Kang Q, Ma J, Han Q, Jin P, Xing R, Lu Y, Sheng J. MicroRNA-135b regulates apoptosis and chemoresistance in colorectal cancer by targeting large tumor suppressor kinase 2. Am J Cancer Res. 2015;5(4):1382-95.(IF=4.165)

    43. Zhu H, Zhao C, Liu F, Wang L, Feng J, Zhou Z, Qu L, Shou C, Yang Z. Radiolabeling and evaluation of (64)Cu-DOTA-F56 peptide targeting vascular endothelial growth factor receptor 1 in the molecular imaging of gastric cancer. American Journal of Cancer Research. 2015;5(11):3301-3310(IF=4.165)

    44. Zhou Z, Zhao C, Wang L, Cao X, Li J, Huang R, Lao Q, Yu H, Li Y, Du H, Qu L, Shou C. A VEGFR1 antagonistic peptide inhibits tumor growth and metastasis through VEGFR1-PI3K-AKT signaling pathway inhibition. Am J Cancer Res. 2015;5(10):3149-61.(IF=4.165)

    45. Shao DF, Wang XH, Li ZY, Xing XF, Cheng XJ, Guo T, Du H, Hu Y, Dong B, Ding N, Li L, Li S, Li QD, Wen XZ, Zhang LH, Ji JF. High-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancer. Am J Cancer Res. 2015;5(2):589-602.(IF=4.165)

    46. Zhang L, Zhang J, Ma Y, Chen J, Dong B, Zhao W, Wang X, Zheng Q, Fang F, Yang Y. Testicular orphan receptor 4 (TR4) is a marker for metastasis and poor prognosis in non-small cell lung cancer that drives the EMT phenotype. Lung Cancer. 2015;89(3):320-8.(3.958)

    47. Zhang L, Xu Y, Jin X, Wang Z, Wu Y, Zhao D, Chen G, Li D, Wang X, Cao H, Xie Y, Liang Z. A circulating miRNA signature as a diagnostic biomarker for non-invasive early detection of breast cancer. Breast Cancer Res Treat. 2015;154:423-434.(IF=3.94)

    48. Feng Y, Huang R, He Y, Lu A, Fan Z, Fan T, Qi M, Wang X, Cao W, Wang X, Xie Y, Wang T, Li J, Ouyang T. Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer. Breast Cancer Res Treat. 2015;149(3):761-5.(IF=3.94)

    49. Zhang XY, Yan WP, Sun Y, Li XT, Chen Y, Fan MY, Wu Y, Liang Z, Xiong HC, Wang ZL, Sun YS, Chen KN. CT Signs Can Predict Treatment Response and Long-Term Survival: A Study in Locally Advanced Esophageal Cancer with Preoperative Chemotherapy. Ann Surg Oncol. 2015;22 Suppl 3:1380-7.(IF=3.93)

    50. Tian X, Ye C, Yang Y, Guan X, Dong B, Zhao M, Hao C. Expression of CD147 and matrix metalloproteinase-11 in colorectal cancer and their relationship to clinicopathological features. J Transl Med. 2015;13(1):337.(IF=3.93)

    51. Liu M, Qu H, Bu Z, Chen D, Jiang B, Cui M, Xing J, Yang H, Wang Z, Di J, Chen L, Zhang C, Yao Z, Zhang N, Tan F, Gu J, Li Z, Su X. Validation of the Memorial Sloan-Kettering Cancer Center Nomogram to Predict Overall Survival After Curative Colectomy in a Chinese Colon Cancer Population. Ann Surg Oncol. 2015;22(12):3881-7.(IF=3.93)

    52. Wang L, Li ZY, Li ZW, Li YH, Sun YS, Ji JF, Gu J, Cai Y. Efficacy and safety of neoadjuvant intensity-modulated radiotherapy with concurrent capecitabine for locally advanced rectal cancer. Dis Colon Rectum. 2015;58(2):186-92.(3.749)

    53. Xing R, Li W, Cui JT, Xia N, Lu YY. GKN1 inhibits cell invasion in gastric cancer by inactivating the NF-kappaB pathway. Discov Med. 2015;19(103):65-71.(IF=3.626)

    54. Ma Y, Fan M, Dai L, Kang X, Liu Y, Sun Y, Yan W, Liang Z, Xiong H, Chen K. The expression of TTF-1 and Napsin A in early-stage lung adenocarcinoma correlates with the results of surgical treatment. Tumour Biol. 2015;36(10):8085-92.(IF=3.611)

    55. Xue Y, Wu L, Liu Y, Ma Y, Zhang L, Ma X, Yang Y, Chen J. ENTPD5 Induces Apoptosis in Lung Cancer Cells via Regulating Caspase 3 Expression. PLoS One. 2015;10(3):e0120046.(IF= 3.53)

    56. Zhao C, Su Y, Zhang J, Feng Q, Qu L, Wang L, Liu C, Jiang B, Meng L, Shou C. Fibrinogen-derived fibrinostatin inhibits tumor growth through anti-angiogenesis. Cancer Sci. 2015;106:1596-1606(IF=3.523)

    57. Zhan J, Wang P, Niu M, Wang Y, Zhu X, Guo Y, Zhang H. High expression of transcriptional factor HoxB9 predicts poor prognosis in patients with lung adenocarcinoma. Histopathology. 2015;66(7):955-65.(IF=3.453)

    58. Zhang C, Liu F, Deng Q, He Z, Xi L, Liu Y, Pan Y, Ning T, Guo C, Xu R, Zhang L, Cai H, Ke Y. Seroprevalence of 10 human papillomavirus types in the general rural population of Anyang, China: a cross-sectional study. Sex Transm Infect. 2015;91(7):506-9.(IF=3.401)

    59. Xu Y, Peng Z, Li Z, Lu M, Gao J, Li Y, Li Y, Shen L. Expression and clinical significance of c-Met in advanced esophageal squamous cell carcinoma. BMC Cancer. 2015;15(1):6.(IF=3.362)

    60. Li D, Zhang J, Xi Y, Zhang L, Li W, Cui J, Xing R, Pan Y, Pan Z, Li F, Lu Y. Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer. BMC Cancer. 2015;15:637.(IF=3.362)

    61. Liu Y, Xu Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y. Association between CHEK2 H371Y mutation and response to neoadjuvant chemotherapy in women with breast cancer. BMC Cancer. 2015;15:194.(IF=3.362)

    62. Xiang Zheng, Jing Zhou, Baozhen Zhang, Jun Zhang, James Wilson, Liankun Gu, Budong Zhu, Jin Gu, Jiafu Ji, Dajun Deng. Critical evaluation of Cbx7 downregulation in primary colon carcinomas and its clinical significance in Chinese patients. BMC Cancer 2015;15:145 (IF=3.362)

    63. Su HJ, Zhang Y, Zhang L, Ma JL, Li JY, Pan KF, You WC. Methylation status of COX-2 in blood leukocyte DNA and risk of gastric cancer in a high-risk Chinese population. BMC Cancer. 2015;15(1):979.(IF=3.362)

    64. Zhu Y, Tian T, Zou J, Wang Q, Li Z, Li Y, Liu X, Dong B, Li N, Gao J, Shen L. Dual PI3K/mTOR inhibitor BEZ235 exerts extensive antitumor activity in HER2-positive gastric cancer. BMC Cancer. 2015;15(1):894.(IF=3.362)

    65. Li H, Shen LY, Yan WP, Dong B, Kang XZ, Dai L, Yang YB, Fu H, Yang HL, Zhou HT, Huang C, Liang Z, Xiong HC, Chen KN. Deregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo. PLoS One. 2015;10(6):e0130551.(IF=3.234)

    66. Jia YM, Xie YT, Wang YJ, Han JY, Tian XX, Fang WG. Association of Genetic Polymorphisms in CDH1 and CTNNB1 with Breast Cancer Susceptibility and Patients' Prognosis among Chinese Han Women. PLoS One. 2015;10(8):e0135865.(IF=3.234)

    67. Li WH, Qiu Y, Zhang HQ, Tian XX, Fang WG. P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway. PLoS One. 2015;10(7):e0133165.(IF=3.234)

    68. Liu X, Jiang B, Wang A, Di J, Wang Z, Chen L, Su X. GATA2 rs2335052 Polymorphism Predicts the Survival of Patients with Colorectal Cancer. PLoS One. 2015;10(8):e0136020.(IF=3.234)

    69. Pan CS, Liu YH, Liu YY, Zhang Y, He K, Yang XY, Hu BH, Chang X, Wang MX, Wei XH, Fan JY, Wu XM, Han JY. Salvianolic Acid B Ameliorates Lipopolysaccharide-Induced Albumin Leakage from Rat Mesenteric Venules through Src-Regulated Transcelluar Pathway and Paracellular Pathway. PLoS One. 2015;10(5):e0126640.(IF=3.234)

    70. Xue Y, Wu L, Liu Y, Ma Y, Zhang L, Ma X, Yang Y, Chen J. ENTPD5 Induces Apoptosis in Lung Cancer Cells via Regulating Caspase 3 Expression. PLoS One. 2015;10(3):e0120046.(IF=3.234)

    71. Wu X, Li Z, Li Z, Jia Y, Shan F, Ji X, Bu Z, Zhang L, Wu A, Ji J. Hyperthermic intraperitoneal chemotherapy plus simultaneous versus staged cytoreductive surgery for gastric cancer with occult peritoneal metastasis. J Surg Oncol. 2015;111(7):840-7.(IF=3.224)

    72. Cheng X, Zheng Z, Bu Z, Wu X, Zhang L, Xing X, Wang X, Hu Y, Du H, Li L, Li S, Zhou R, Wen XZ, Ji JF. LAPTM4B-35, a cancer-related gene, is associated with poor prognosis in TNM stages I-III gastric cancer patients. PLoS One. 2015;10(4):e0121559.(IF=3.234)

    73. She T, Zhao C, Feng J, Wang L, Qu L, Fang K, Cai S, Shou C. Sarsaparilla (Smilax Glabra Rhizome) extract inhibits migration and invasion of cancer cells by suppressing TGF-β1 pathway. PLoS One. 2015;10(3):e0118287.(IF=3.234)

    74. Pei X, Li M, Zhan J, Yu Y, Wei X, Guan L, Aydin H, Elson P, Zhou M, He H, Zhang H. Enhanced IMP3 Expression Activates NF-кB Pathway and Promotes Renal Cell Carcinoma Progression. PLoS One. 2015;10(4):e0124338.(IF=3.234)

    75. Li ZX, Wang YM, Tang FB, Zhang L, Zhang Y, Ma JL, Zhou T, You WC, Pan KF. NOD1 and NOD2 Genetic Variants in Association with Risk of Gastric Cancer and Its Precursors in a Chinese Population. PLoS One. 2015;10(5):e0124949.(IF=3.234)

    76. Qi L, Yu Y, Chi X, Xu W, Lu D, Song Y, Zhang Y, Zhang H. Kindlin-2 interacts with α-actinin-2 and β1 integrin to maintain the integrity of the Z-disc in cardiac muscles. FEBS Lett. 2015;589(16):2155-62.(IF=3.169)

    77. Liu Z, Lu D, Wang X, Wan J, Liu C, Zhang H. Kindlin-2 phosphorylation by Src at Y193 enhances Src activity and is involved in Migfilin recruitment to the focal adhesions. FEBS Lett. 2015;589(15):2001-2010(IF=3.169)

    78. Han SY, Zhao W, Sun H, Zhou N, Zhou F, An G, Li PP. Marsdenia tenacissima extract enhances gefitinib efficacy in non-small cell lung cancer xenografts. Phytomedicine. 2015;22(5):560-7(IF=3.126)

    79. Lv C, An C, Feng Q, Ma Y, Li S, Wang J, Zhang J, Wang X, Yan S, Fang J, Wang Y, Tan F, Yang Y. A Retrospective Study of Stage I to IIIa Lung Adenocarcinoma After Resection: What Is the Optimal Adjuvant Modality for Patients With an EGFR Mutation? Clin Lung Cancer. 2015;16(6):e173-81.(IF=3.104)

    80. Zhang Q, Zhu M, Cheng W, Xing R, Li W, Zhao M, Xu L, Li E, Luo G, Lu Y. Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer. J Cancer Res Clin Oncol. 2015;141(4):691-703.(IF=3.081)

    81. Li XT, Tang L, Chen Y, Li YL, Zhang XP, Sun YS. Visceral and subcutaneous fat as new independent predictive factors of survival in locally advanced gastric carcinoma patients treated with neo-adjuvant chemotherapy. J Cancer Res Clin Oncol. 2015;141(7):1237-47.(IF=3.081)

    82. Weiben Yong. Clinical study of L-asparaginase in the treatment of extranodal NK/T-cell lymphoma, nasal type. Hematological Oncology 2015 Apr 21.doi:10.1002/hon.2207   (IF=3. 08)

    83. Ji F, Chang X, Liu C, Meng L, Qu L, Wu J, Liu C, Cui H, Shou C. Prognostic value and characterization of the ovarian cancer-specific antigen CA166-9. Int J Oncol. 2015;47(4):1405-15.(IF=3.025)

    84. Tang FB, Li ZX, Wang YM, Zhang L, Ma JL, Zhou T, Zhang Y, Gao JJ, Wu S, Yang T, You WC, Pan KF. Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population. Infect Genet Evol. 2015;31:263-9.(IF=3.015)

    85. Wu XJ, Miao RL, Li ZY, Bu ZD, Zhang LH, Wu AW, Zong XL, Li SX, Shan F, Ji X, Ren H, Ji JF. Prognostic value of metastatic lymph node ratio as an additional tool to the TNM stage system in gastric cancer. Eur J Surg Oncol. 2015;41(7):927-33.(IF=3.009)