陆明 男 北京肿瘤医院消化肿瘤内科的主任医师、副教授、硕士生指导老师，2009年毕业于北京大学临床肿瘤学院，获肿瘤学博士学位，从事肿瘤临床工作近20年。擅长消化系统肿瘤包括神经内分泌肿瘤、胃癌、食管癌、肠癌、胰腺癌、等病种的个体化和多学科综合治疗，具有丰富的临床经验。熟悉各领域的国际最新进展，研究方向主要专注于神经内分泌肿瘤的分子分型、个体化多学科治疗和转化治疗等。参与几十项国内国际临床研究的病例入组和诊治管理工作。以第一/通讯作者在Clinical cancer research、Cancer、Cancer communications、Cancer science、Oncotarget、Medicine等杂志发表相关论文十余篇。主持国家级和省部级基金课题2项。获中国抗癌协会科技一等奖、北京大学首届临床医疗奖等。

社会兼职：中国临床肿瘤学会(CSCO)神经内分泌肿瘤委员会委员;中国医疗保健国际交流促进会神经内分泌肿瘤分会委员;中国医学前沿杂志(电子版)编辑委员会编辑部部主任。

代表性论文、专著及专利情况

1. Ming Lu, Panpan Zhang (joint first author), Lin Shen, et al, Efficacy, safety and biomarkers of toripalimab in patients with recurrent or metastatic neuroendocrine neoplasms: a multiple-center phase Ib trial. (Clinical Caner Research. IF 10.199);

2. Panpan Zhang, Jie Li, Lin Shen, Ming Lu, et al. Etoposide and cisplatin versus irinotecan and cisplatin as the first-line therapy for advanced poorly differentiated gastroenteropancreatic neuroendocrine carcinoma: a randomized phase II study. (Cancer. IF 6.102)

3. Yansuo Cao, Yutong Ma, Jiangyuan Yu……Ming Lu. Favorable response to immunotherapy in a pancreatic neuroendocrine tumor with temozolomide-induced high tumor mutational burden. Cancer Communications. 2020;1–6.

4. Li Jie Lu M, ZH Lu et al. Irinotecan plus cisplatin followed by octreotide long-acting release maintenance treatment in advanced gastroenteropancreatic neuroendocrine carcinoma：IPO-NEC Study. Oncotarget.2016.

5. Panpan Zhang Jiangyuan Yu,Jie Li, Lin Shen , Nan Li, Hua Zhu, Shizhen Zhai,Yan Zhang, Zhi Yang, and Ming Lu. Clinical and Prognostic Value of PET/CT Imaging with Combination of 68Ga-DOTATATE and 18F-FDG in Gastroenteropancreatic Neuroendocrine Neoplasms. Contrast Media & Molecular Imaging. 2018 Feb 26;2018:2340389.

6. Lu M, Wang X, Shen L et al. Nimotuzumab Plus Paclitaxel and Cisplatin as the 1st Line Treatment for Advanced Esophageal Squamous Cell Cancer (ESCC): a Single Centre Prospective Phase II Trial. Cancer Sci. 2016 Apr;107(4):486-90.

7. Lu, Ming; Yang, Zuyao; Feng, Qi et al. The characteristics and prognostic value of signet ring cell histology in gastric cancer: A retrospective cohort study of 2199 consecutive patients. Medicine, 2016, 95(27): e4052

8. 刘丹, 陆明.胃神经内分泌肿瘤的诊断和治疗. 临床肿瘤学杂志. 2015;20(6):549-554

9. 陆明.胃肠道神经内分泌癌(WHO G3)的异质性和个体化治疗. 中国医学前沿杂志(电子版). 2014;6(11):16-19

10. 陆明,沈琳.晚期胰腺神经内分泌肿瘤的综合治疗. 中国实用外科杂志. 2014;34(6):19-23