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胃肠肿瘤中心二病区 - 王安强

王安强简介

医学博士,毕业于北京协和医学院北京协和医院,中国医学科学院&北京协和医学院优秀博士论文获得者,北京大学医学部校级优秀住院医师,美国癌症研究协会会员,中国医疗保健国际交流促进会结直肠病学分会委员,北京市慢性病防治与健康教育研究会胃肠疾病专业委员会委员。主要从事胃肠肿瘤的临床诊疗工作,同时从事胃癌的分子分型,肿瘤克隆进化,淋巴结转移及胃肠罕见肿瘤等相关基础研究。目前负责多项临床及基础研究,主持国家自然科学基金青年基金,首都卫生发展基金青年优才等多项基金。在Science,Nature communications, Theranostics,Oncogene,Genome medicine, Nucleic Acids Research, Ebiomedicine等多个国内外知名期刊发表学术论文数十篇。曾受邀参加2019年AACR,2019年世界胃癌大会(IGCC)等多个国内外学术会议进行学术交流,并荣获2019年世界胃癌大会“Young Investigator Diploma”称号。2019年入选北京市医管局青苗人才计划。

发表论文

1. Zheng L#, Qin S#, Si W#, Wang A, Xing B, Gao R, Ren X,

Wang L, Wu X, Zhang J et al: Pan-cancer single-cell landscape of tumor-infiltrating T cells. Science (New York, NY) 2021, 374(6574):abe6474.

2. Wang A, Wu L, Lin J, Han L, Bian J, Wu Y, Robson SC, Xue

L, Ge Y, Sang X et al: Whole-exome sequencing reveals the origin and evolution of hepato-cholangiocarcinoma. Nat Commun 2018, 9(1):894.

3. Wang A, Li Z, Wang M, Jia S, Chen J, Ji K, Ji X, Zong X, Wu

X, Zhang J et al: Molecular characteristics of synchronous multiple gastric cancer. Theranostics 2020, 10(12):5489-5500.

4. Sun C#, Wang A#, Zhou Y#, Chen P, Wang X, Huang J, Gao J,

Wang X, Shu L, Lu J, Dai W#, Bu Z#, Ji J#, He J#. Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nature communications 2023, 14(1):2692.

5. Liu Z#, Wang A#, Pu Y#, Li Z#, Xue R, Zhang C, Xiang X, E

JY, Bu Z, Bai F et al: Genomic and transcriptomic profiling of hepatoid adenocarcinoma of the stomach. Oncogene 2021, 40(38):5705-5717.

6. Long J#, Wang D,# Wang A#, et al. A mutation-based gene

set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape. Genome medicine 2022; 14(1): 20.

7. Yang Z#, Wu L#, Wang A#, Tang W, Zhao Y, Zhao H,

Teschendorff AE: dbDEMC 2.0: updated database of differentially expressed miRNAs in human cancers. Nucleic Acids Res 2017, 45(D1):D812-d818.

8. Wang A, Li Z, Wang Q, Bai Y, Ji X, Fu T, Ji K, Xue Y, Han T,

Wu X et al: Diagnostic value of negative enrichment and immune fluorescence in situ hybridization for intraperitoneal free cancer cells of gastric cancer. Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2019, 31(6):945-954.

9. Zhou K#, Wang A#, Ao S#, Chen J, Ji K, He Q, Ji X, Wu X,

Zhang J, Li Z et al: The prognosis of hepatoid adenocarcinoma of the stomach: a propensity score-based analysis. BMC cancer 2020, 20(1):671.

10. Chen J#, Wang A#, Ji K#, Bu Z, Ji J: Comparison of overall

survival of gastric neoplasms containing neuroendocrine carcinoma components with gastric adenocarcinoma: a propensity score matching study. BMC cancer 2020, 20(1):777.

11. Chen J#, Wang A#, Ji J#, Zhou K, Bu Z, Lyu G, Ji J: An

Innovative Prognostic Model Based on Four Genes in Asian Patient with Gastric Cancer. Cancer research and treatment : official journal of Korean Cancer Association 2020. Jan;53(1):148-161.

12. Zhou K#, Wang A#, Wei J#, Ji K, Li Z, Ji X, Fu T, Jia Z, Wu X,

Zhang J et al: The Value of Perioperative Chemotherapy for Patients With Hepatoid Adenocarcinoma of the Stomach Undergoing Radical Gastrectomy. Frontiers in oncology 2021, 11:789104.