北京大学肿瘤医院

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胃肠肿瘤中心二病区 - 季科

季科简介

中共党员,毕业于英国卡迪夫大学医学院获得肿瘤学(外科)博士学位。现任胃肠肿瘤中心二病区主治医师。

目前主要从事消化道肿瘤,包括胃癌、食管为结合部腺癌、结肠癌、直肠癌、胃肠道间质瘤等消化道肿瘤的外科治疗、围手术期药物治疗。擅长胃肠道肿瘤的规范化治疗及微创外科治疗。

学术方面,以第一作者发表中英文章20余篇,并多次于国际、国家级会议进行演讲、壁报展示,参编参译论著多部。目前承担北京市属医院科研培育计划项目,参与多项科研课题,如国自然科学基金面上项目、北京市医管中心培育计划项目、北大医学青年科技创新培育基金项目等。作为研究者参与多项全国多中心、大型临床研究项目。

发表论文

1.Fu T, Ji K, Jin L, Zhang J, Wu X, Ji X, Fan B, Jia Z, Wang A, Liu J, Bu Z, Ji J. ASB16-AS1 up-regulated and phosphorylated TRIM37 to activate NF-κB pathway and promote proliferation, stemness, and cisplatin resistance of gastric cancer. Gastric Cancer. 2021 Jan;24(1):45-59. Doi:10.1007/s10120-020-01096-y. Epub 2020 Jun 22. PMID:32572790

2.Fan B, Ji K, Bu Z, Zhang J, Yang H, Li J, Wu X. ARHGAP11A is a Prognostic Biomarker and Correlated with Immune Infiltrates in Gastric Cancer. Front Mol Biosci. 2021 Oct 18;8:720645. doi: 10.3389/fmolb.2021.720645. eCollection 2021. PMID:34733886

3.Ji X, Jin C, Ji K, Zhang J, Wu X, Jia Z, Bu Z, Ji J. Double Tract Reconstruction Reduces Reflux Esophagitis and Improves Quality of Life After Radical Proximal Gastrectomy for Patients with Upper Gastric or Esophagogastric Adenocarcinoma. Cancer Res Treat. 2021 Jul;53(3):784-794. doi: 10.4143/crt.2020.1064. Online ahead of print. PMID: 33421979

4.Ji K, Ao S, He L, Zhang L, Feng L, Lyu G. Characteristics of cancer susceptibility genes mutations in 282 patients with gastric adenocarcinoma. Chin J Cancer Res. 2020Aug;32(4):508-515.Doi:10,21147/j.issn.1000-9604.2020.04.08. PMID:32963463

5.Ji K, Ye L, Sun PH, Hargest R, Mason M and Jiang WG. Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer. BMC Cancer, 2014 Sep 27; 14:723. DOI: 10.1186/1471-2407-14-723.

6.Ji K, Ye L, Mason M and Jiang WG. The Kiss‑1/Kiss‑1R complex as a negative regulator of cell motility and cancer metastasis. International Journal of Molecular Medicine, 2013 Oct;32(4):747-54. DOI: 10.3892/ijmm.2013.1472. Epub 2013 Aug 21. Review.

7.Ji K, Ye J, Toms AM, Hargest R, Martin TA, Ruge F, Ji JF, Jiang WG. Expression of Signal-induced proliferation-associated gene 1 (SIPA1), a RapGTPase-activating protein is increased in colorectal cancer and has diverse effects on functions of colorectal cancer cells. Cancer Genomics and Proteomics, 2012, 9(5), 321-7.