北京大学肿瘤医院

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胃肠肿瘤中心一病区 - 贾永宁

贾永宁简介

教育背景:北京大学医学部博士毕业,2013.5-2014.5于英国卡迪夫大学博士后研究;

学术方向:进展期胃癌围术期药物治疗联合根治手术的综合治疗;

科研成果:承担国家青年自然科学基金一项,北京市医院管理局青年人才培养“青苗”计划;第一作者发表SCI文章10篇,累计IF 103分;

临床工作:进展期胃癌的围手术期药物治疗(化疗,靶向,免疫治疗)以及腹腔镜微创手术、全腹腔镜下消化道重建,尤其是胃食管结合部癌的术前药物治疗联合微创手术,胃的功能保留以及高位吻合。合并肝转移、腹主动脉旁淋巴结转移的晚期胃癌药物转化治疗以及手术。结直肠癌以及低位直肠癌的微创手术,晚期结肠癌的多学科协作以及转化治疗后手术治疗;胃肠道间质瘤,神经内分泌癌的药物治疗联合手术等。

发表论文

第一作者发表文章

Gao X, Ji K, Jia Y, et al. Cadonilimab with chemotherapy in HER2-negative gastric or gastroesophageal junction adenocarcinoma: the phase 1b/2 COMPASSION-04 trial. Nat Med. 2024. 30(7): 1943-1951  IF:58.7

Wang Y, Gan X, Cheng X, et al. ABCC2 induces metabolic vulnerability and cellular ferroptosis via enhanced glutathione efflux in gastric cancer. Clin Transl Med. 2024. 14(8): e1754.  IF:7.9

Li, Ziyu#; Jia, Yongning#; Zhu, Honglin #; Yuan, Hongling; Xing, Xiaofang; Xin, Yaqun; Ma, Tonghui; Pang, Fei; Zhang, Yan; Hu, Ying; Jia, Shuqin*; Ji, Jiafu*,Genomic landscape of microsatellite instability in Chinese tumors: a comparison of Chinese and TCGA cohorts, International Journal of Cancer,2022,IF:5.507

Xing X#;Shi J#;Jia Y#;Dou Y;Li Z;Dong B;Guo T;Cheng X;Li X;Du H;Hu Y;Jia S*;Zhang J*;Li Z*;Ji J*; Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis. Journal for immunotherapy of cancer,2022, IF:10.9

Li Z#;Jia Y#;Zhu H#;Xing X#;Pang F;Shan F;Li S;Wang D;Zhao F;Ma T;Wang S; Ji J*; Tumor mutation burden is correlated with response and prognosis in microsatellite-stable (MSS) gastric cancer patients undergoing neoadjuvant chemotherapy. Gastric Cancer ,2021,IF:6.253

Jia Y#;Li Z#;Cheng X;Wu X;Pang F;Shi J;Li S;Li X;Hu Y;Zhang L;Ji J*,Depletion of death-associated protein-3 induces chemoresistance in gastric cancer cells through the β-catenin/LGR5/Bcl-2 axis. Journal of investigative medicine,2019,  IF:2.3

Jia Y, Ye L, Ji K, et al. Death-associated protein-3, DAP-3, correlates with preoperative chemotherapy effectiveness and prognosis of gastric cancer patients following perioperative chemotherapy and radical gastrectomy. Br J Cancer. 2014. 110(2): 421-9 IF:4.84

参与发表文章:

Yin S;Xi R;Wu A;Wang S;Li Y;Wang C;Tang L;Xia Y;Yang D;Li J;Ye B;Yu Y;Wang J;Zhang H;Ren F;Zhang Y;Shen D;Wang L;Ying X;Li Z;Bu Z;Ji X;Gao X;Jia Y;Jia Z;Li N;Li Z;Ji JF;Xi JJ; Patient-derived tumor-like cell clusters for drug testing in cancer therapy. Science translational medicine,2020,IF:17.96